We aimed to characterise the association of pulmonary hypertension due to hypoventilation and exercise capacity, and the haemodynamic and functional changes under noninvasive ventilation. A retrospective analysis was carried out to assess haemodynamics and functional capacity in 18 patients with daytime pulmonary hypertension, due to hypoventilation, at baseline and after 3 months of noninvasiv...

Since the first report of successful "late" embolectomy for recurrent pulmonary embolism,' a number of patients have been described with significant pulmonary hypertension where clinical improvement associated with lowering of pulmonary artery pressure has followed removal of extensive, well-organised thrombo-embolic material from major pulmonary vessels.2 The following case history illustrates...

Pulmonary hypertension is uncommonly associated with portal hypertension. The current approach for the management of pulmonary hypertension involves the use of vasodilators in patients who show vascular responsiveness during an acute challenge. Since the association of portal hypertension with pulmonary hypertension is very seldomly presented, its optimal therapy has not been defined. Moreover,...

Magnetic resonance imaging (MRI) can provide accurate anatomical measurements of the cardiac ventricles. This study investigated whether a calculated ventricular mass index (VMI) would provide an accurate means of estimating pulmonary artery pressure noninvasively, and compared the results with conventional Doppler echocardiography and invasive measurement. A total of 26 subjects referred for i...

BACKGROUND Schistosomiasis is a highly prevalent disease with >200 million infected people. Pulmonary hypertension is one of the pulmonary manifestations in this disease, particularly in its hepatosplenic presentation. The aim of this study was to determine the prevalence of pulmonary hypertension in schistosomiasis patients with the hepatosplenic form of the disease. METHODS AND RESULTS All ...

A 68-year-old woman with long-standing severe pulmonary arterial hypertension was referred for coronary catheterization for investigation of worsening exertional dyspnea associated with angina. Coronary angiography revealed critical ostial left main coronary artery (LMCA) stenosis. Given the history of severe pulmonary arterial hypertension, simultaneous angiography of the LMCA and main pulmona...

Pulmonary hypertension frequently complicates mitral stenosis. Increased pulmonary artery pressure results from raised left atrial pressure, pulmonary arteriolar constriction, and obliterative changes in the pulmonary vascular bed, and usually responds to surgical relief of mitral stenosis. However, severe pulmonary hypertension may persist after surgical treatment of mitral stenosis. We descri...

UNLABELLED Cardiac catheterization is the reference method for the hemodynamic study of the pulmonary circulation. However, cardiac catheterization is an expensive and invasive method. Echocardiography is a reliable noninvasive alternative method. The purpose of our study was to determine the correlation between echocardiographic and haemodynamic data obtained by cardiac catheterization in pati...

conclusions the etiology of pah in thalassemia is multifactorial such as inflammatory mediators. also, the absence of the spleen plays an important role in developing a high trv and pah. results average age of the patients was 21.15 ± 6.68 years. no significant difference was observed in the pap between the 2 groups of thalassemia major and intermedia and also the 2 sex groups. indeed, 6.6% of ...

OBJECTIVE To investigate the influence of Fasudil, a Rho inhibitor on the number and functions of the late endothelial progenitor cells in peripheral blood of chronic obstructive pulmonary diseases (COPD) patients with pulmonary artery hypertension. BACKGROUND It is not clear yet, whether Rho Kinase Inhibitor Fasudil can reduced pulmonary artery pressure through improving lung endothelial fun...