Echinococcus granulosus sensu lato larvae cause cystic echinococcosis, a highly contagious zoonotic illness that poses worldwide threat to human health and development. The purpose of this study was determine the therapeutic effectiveness albendazole praziquantel, each alone in combination, vivo estimate serum levels interleukin-2, interleukin-9 interleukin-10 as biomarkers evaluating responsiv...

AIM Cystic echinococcosis (CE) has potential economic effects to both animal products and human health. A vaccine to protect livestock against CE can be effective in reducing economic costs and increasing the livestock products. Protoscolex tegumental surface antigens (PSTSA) used to induce the production of specific antibodies against Echinococcus granulosus in sheep. The tegumental antigens w...

In this study, we designed an experiment to predict a potential immunodominant T-cell epitope and evaluate the protectivity of this antigen in immunised mice. The T-cell epitopes of the candidate proteins (EgGST, EgA31, Eg95, EgTrp and P14-3-3) were detected using available web-based databases. The synthesised DNA was subcloned into the pET41a+ vector and expressed in Escherichia coli as a fusi...

Objective: Cystic echinococcosis (CE) is an important parasitic infection caused by Echinococcus granulosus (E. granulosus) larvae, adults of which live in Canidae. Although CE observed all over the world, it more prevalent developing and underdeveloped nations.
 Material Method: This study was conducted on a total 60 cyst samples, including 20 sheep cattle slaughtered abattoir patients op...