The detailed solvation structure at the (110) surface of rutile (alpha-TiO2) in contact with bulk liquid water has been obtained primarily from experimentally verified classical molecular dynamics (CMD) simulations of the ab initio-optimized surface in contact with SPC/E water. The results are used to explicitly quantify H-bonding interactions, which are then used within the refined MUSIC model...

Intermolecular interactions involving carbohydrates and their natural receptors play important roles in several biological processes. The development of synthetic receptors is very useful to study these recognition processes. Recently, it was synthetized a diaminopyrrolic tripodal receptor that is selective for mannosides, which are obtained from mannose, a sugar with significant relevance in l...

The photo-oxidation of purine nucleotides adenosine-5'-monophosphate (AMP) and guanosine-5'-monophosphate (GMP) by 3,3',4,4'-benzophenone tetracarboxylic acid (TCBP) has been investigated in aqueous solutions using nanosecond laser flash photolysis (LFP) and time-resolved chemically induced dynamic nuclear polarization (CIDNP). The pH dependences of quenching rate constants and of geminate pola...

An electrometric method was used to investigate the effect of pH and ionic strength on the second flash-induced formation of the transmembrane electric potential difference (A~b) arising from proton uptake by the quinone complex of the photosynthetic reaction center (RC) in chromatophores of non-sulphur purple bacterium Rhodobacter sphaeroides (wild-type). The characteristic time of this A~b ph...

Insolubilized cr-chymotrypsin bound to porous glass gel has been prepared. The kinetic behavior of this fixed enzyme proved to be the same as that of the free enzyme. The effects of aprotic dipolar organic solvents on the kinetics of cr-chymotrypsin-catalyzed hydrolysis were successfully studied using this insolubilized enzyme at concentrations up to 95% v/v dioxane, taking advantage of the ina...

bacteria of the genus azospirillum are well known as plant growth promoting rhizobacteria. the ability to synthesize phytohormones is considered one of the most important mechanisms to promote plant growth and is widely distributed among plant-associated rhizobacteria.the most important phytohormone produced by azospirillum is the auxin indole-3-acetic acid, with the l-tryptophan as the precurs...

indoleamine 2,3-dioxygenase (ido), an enzyme involved in the catabolism of tryptophan, is expressed by a variety of cells and tissues such as macrophages, dendritic cells, cells of the endocrine system and by the placenta. ifn- γ is the main inducer of this enzyme. ido acts as an important defense mechanism of innate immunity against pathogens. it also has tumor suppressive activity and prolong...

To obtain a better understanding of the mycorrhizas as an elicitor, and precursor feeding effects on the protein content and TIAs biosynthesis in Catharanthus roseus L., foliar application of four concentrations of tryptophan (0, 150, 250 and 350 mg/l) on some growth parameters and chemical compositions of mycorrhizal plants were investigated. The results revealed that the total protein content...

p53 tumor suppressor gene, also known as “genome guardian” is mutated in more than half of allkind of cancers. in this study we have investigated the controls of environmental ph for p53 genemutation in point of specific sequence which is prone to mutagenesis. the most probable cancerousmutations occur as point mutations in exons 5-8 of p53 gene. the 175th codon of p53 is the thirdmost mutated ...