BACKGROUND There have been few reports about high total dose hypofractionated proton beam therapy for central lung cancer. The aim of this study was to examine retrospectively the safety and efficacy of high total dose hypofractionated proton beam therapy for central lung cancer. PATIENTS AND METHODS Patients treated by proton beam therapy for central lung cancer located less than 2 cm from t...

Introduction: The main advantage of using ion beams over photons in radiotherapy is due to their inverse depth-dose profiles, allowing higher doses to tumors, while better sparing normal tissues. When calculating dose distributions with ion beams, one crucial point is the uncertainty of the Bragg-peak range. Recently great effort is devoted to enhance the accuracy of the comput...

The DoPET project (Dosimetry with a Positron Emission Tomograph) funded by INFN aims to realize an inbeam PET system dedicated [1]. The system has been validated through measurements on PMMA phantoms, in the perspective of clinical application in proton therapy monitoring at CATANA. Differences in proton-induced activity distribution down to 1 mm along the proton range have been appreciated [2]...

The microscopic dynamics of an excess proton in water and in low-density amorphous ices has been studied by means of a series of molecular dynamics simulations. Interaction of water with the proton species was modelled using a multistate empirical valence bond Hamiltonian model. The analysis of the effects of low temperatures on proton diffusion and transfer rates has been considered for a temp...

introduction proton therapy is used to treat malignant tumors such as melanoma inside the eye. proton particles are adjusted according to various parameters such as tumor size and position and patient’s distance from the proton source. the purpose of this study was to assess absorbed doses in eyes and various tumors found in the area of sclera and choroid and the adjacent tissues in radiotherap...

The production of η mesons has been measured in the proton-proton interaction close to the reaction threshold using the COSY-11 internal facility at the cooler synchrotron COSY. Total cross sections were determined for eight different excess energies (ǫ) in the range from ǫ = 0.5 MeV to ǫ = 5.4 MeV. The energy dependence of the total cross section is well described by the available phase–space ...