The plant response to sulfur deficiency includes extensive metabolic changes which can be monitored at various levels (transcriptome, proteome, metabolome) even before the first visible symptoms of sulfur starvation appear. Four members of the plant-specific LSU (response to Low SUlfur) gene family occur in Arabidopsis thaliana (LSU1-4). Variable numbers of LSU genes occur in other plant specie...

Coenzyme Q10 (CoQ10) is essential for the energy production of the cells and as an electron transporter in the mitochondrial respiratory chain. CoQ10 links the mitochondrial fatty acid β-oxidation to the respiratory chain by accepting electrons from electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO). Recently, it was shown that a group of patients with the riboflavin responsive f...

oxidative stress has been implicated in the progression of hiv to aids, since hiv usually replicates in a highly oxidized condition and cd4+ t lymphocytes can be activated via a cascade of internal oxidative pathways, which enhances the formation of proteins and enzymes. thus, antioxidants should potentially be useful for the treatment and prevention of hiv infection as a new alternative strate...

Extensive changes in plant transcriptome and metabolome have been observed by numerous research groups after transferring plants from optimal conditions to sulfur (S) deficiency. Despite intensive studies and recent important achievements, like identification of SLIM1/EIL3 as a major transcriptional regulator of the response to S-deficiency, many questions concerning other elements of the regul...

Neuronal ceroid lipofuscinoses represent the most common childhood neurodegenerative storage disorders. Infantile neuronal ceroid lipofuscinosis (INCL) is caused by palmitoyl protein thioesterase-1 (PPT1) deficiency. Although INCL patients show signs of abnormal neurotransmission, manifested by myoclonus and seizures, the molecular mechanisms by which PPT1 deficiency causes this abnormality rem...

Selenium (Se) is an important trace element in human and animal health. Approximately 0.5–1 billion people worldwide are facing Se deficiency which can result various endemic diseases. Cabbage one of the most popular vegetables accumulate through biofortification. Therefore, producing Se-enriched cabbage may be effective method to alleviate deficiency. In this study, effects different concentra...