نتایج جستجو برای: protein a
تعداد نتایج: 13718509 فیلتر نتایج به سال:
LOX-1 is a class E scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved in endothelial dysfunctions, monocyte adhesion, the proliferation, migration, and apoptosis of smooth muscle cells, foam cell formation, platelet activation, as well as plaque instability; all of these events are critical in the pathogenesis of atherosclerosis. These LOX-1-dependent bio...
Background and Aim: Annexins are a large family of calcium-phospholipid binding proteins which are distributed among nearly all eukaryotes. These proteins have been found in a wide range of fungi including ascomycetes, basidiomycetes and oomycetes. The aim of present study has been the investigation of cellular localization of ANXC3.1 in filamentous fungus Aspergillus niger (A. niger). The ...
The rotavirus nonstructural protein 4 (NSP4), is a multi functional protein that play key role in both viral morphogenesis and cytopathic effect associated with cell death. However, the complete biological effect of NSP4 remains to be clarified. Since to obtain further knowledge about this protein there is a need for recognizing antibody and there is no commercial antibody against this protein,...
Estimation of protein stability is important for many reasons: first providing an understanding of the basic thermodynamics of the process of folding, protein engineering, and protein stability plays important role in biotechnology especially in food and protein drug design. Today, proteins are used in many branches, including industrial processes, pharmaceutical industry, and medical fields. A...
background: the herpes simplex virus (hsv) ul41 gene product, virion host shutoff (vhs) protein, mediates the rapid degradation of both viral and cellular mrna. this ability suggests that vhs protein can be used as a suicide gene in cancer gene therapy applications. the recent reports have shown that the degradation of cellular mrna during herpes simplex infection is selective. rna containing a...
Risk assessment of a transgene is one of the key steps in genetic transformation. Hence, in order to use cryIAc gene for production of transgenic plants, a library and in-silico research was performed to confirm safety of the gene for human comsumption, animal feed and environment. In the first step, the molecular mechanism of action of the CryIAc protein and its specific receptors in the midgu...
lentiviral vectors are among the promising viral based-vectors in gene therapy applications, but the efficiency of their targeting needs to be improved. (strept)avidin-biotin adaptor system is a novel approach to modify the lentiviral envelope for better targeting properties. herein, we describe utilization of this adaptor system by designing a candidate envelope protein-bearing biotin acceptor...
Calcitonin Gene Related Peptide (CGRP) was first reported in 1982. This peptide contains 37 amino acids which could be found in Alpha and Beta forms. CGRP shows diversity both in its receptors and biological effects and up to now four different types of receptors have been reported. It can act like a neurotransmitter, local hormone and neuromodulator. They have a variety of effects on different...
Lysozyme, as a model protein, was precipitated through the formation of protein-Zn complex to micronize for subsequent encapsulation within poly (lactic-co-glycolic acid) (PLGA) microspheres. Various parameters, including pH, type and concentration of added salts and protein concentration, were modified to optimize the yield of protein complexation and precipitation. The resulting protein parti...
Objective(s): Streptokinase (SKa) is an antigenic protein which is secreted by Streptococcus pyogenes. Streptokinase induces inflammation by complement activation, which may play a role in post infectious diseases. In the present study, recombinant streptokinase from S. pyogenes was produced and showed that recombinant SKa protein was recognized by infected human sera using Western blot analy...
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