BACKGROUND Cervical screening programs are highly protective for cervical cancer, but only for women attending screening procedure. OBJECTIVE Identify socio-economic and demographic determinants for non-attendance in cervical screening. METHODS Design: Population-based case-control study. Setting: Sweden. Population: Source population was all women eligible for screening. Based on complete ...

T h e issues of database security and integrity are tightly related. Security mechanisms and integrity mechanisms are both concerned with protection of information, and both involve management of meta-information and procedures for screening transactions. Yet in database systems these tasks are entirely separate. In this paper we describe a unified model that accommodates both security and inte...

Zika virus (ZIKV) is a mosquito-borne flavivirus distributed all over Africa, South America and Asia. The infection with the virus may cause acute febrile sickness that clinically resembles dengue fever, yet there is no vaccine, no satisfactory treatment, and no means of evaluating the risk of the disease or prognosis in the infected people. In the present study, the efficacy of the host's immu...

A differential serological screen of a lambda gt11 cDNA expression library of Plasmodium falciparum was performed in an attempt to identify novel and putative host-protective antigens of the parasite. The screening was done with two categories of sera: (i) acute-phase sera obtained from smear-positive acutely infected P. falciparum patients from various regions in India and (ii) immune sera tak...

BACKGROUND A challenge facing stakeholders is the identification and translation of relevant high quality research to inform policy and practice. This study engaged academic and community stakeholders in conducting a best evidence-synthesis to identify modifiable risk and protective worker factors across health conditions impacting work-related absence. OBJECTIVES To identify modifiable worke...

Worm transplantation studies show that physiological and reproductive status of the worm is influenced by the microenvironment of the host and critical for vaccine design. Worm migration studies in rats with (75)Se-methionine labeled cercariae demonstrated that resistance to reinfection (R/R) requires a host immune response resulting in worm death. In permissive hosts, inflammation due to anti ...

Epidemiological studies have reported that coffee and/or caffeine consumption may reduce Alzheimer's disease (AD) risk. We found that coffee extracts can similarly protect against β-amyloid peptide (Aβ) toxicity in a transgenic Caenorhabditis elegans Alzheimer's disease model. The primary protective component(s) in this model is not caffeine, although caffeine by itself can show moderate protec...

Protein formulation development relies on the selection of excipients that inhibit protein-protein interactions preventing aggregation. Empirical strategies involve screening many excipient and buffer combinations using force degradation studies. Such methods do not readily provide information on intermolecular interactions responsible for the protective effects of excipients. This study descri...

To test the hypothesis that regional fat and not total body weight has a protective effect on bone mineral density (BMD) in postmenopausal women, a cross-sectional study was conducted during the period from March 2008 to June 2009 on 303 healthy postmenopausal women presenting to the osteoporosis unit for screening purposes. BMD of the lumbar spine, L2-L4, and the neck of the left femur were me...

Objective: To describe behavior problems in children with various chronic illnesses (CI) who seek psychosocial support, and to examine associated risk factors and protective factors. Methods: Parents and children who signed up for a cognitive behavioral based group intervention on coping with CI (N = 194) completed online questionnaires. Multiple linear regression analyses were conducted on int...