Submit Manuscript | http://medcraveonline.com Abbreviations: ANVISA: National Health Surveillance Agency; BHA: mixture of 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl4-hydroxyanisole; BHT: 3,5-di-tert-butyl-4-hydroxytoluene; CGMS: Gaseous Chromatography coupled to Mass Spectrometry; HPLC: High Pressure Liquid Chromatography; PG: Propyl 3,4,5-trihydroxybenzoate or Propyl Gallate; TBHQ: Tertbut...

The metabolism of 7-ethyl- and 7-propyl-chenodeoxycholic acids was studied in hamsters. Both bile acid analogs were absorbed efficiently by the intestine and secreted into the bile at rates similar to those of chenodeoxycholic acid. After intraduodenal administration into bile fistula hamsters, the 7-alkyl analogs were present in bile as the glycine and taurine conjugates. The glycine/taurine r...

The title compound, C(13)H(16)N(2)O(3)S, is a thio-urea derivative with benzoyl and propoxycarbonyl-methyl groups attached to the two terminal N atoms. These groups adopt trans and cis configurations, respectively, with respect to the S atom across the thio-urea C-N bonds. The compound crystallizes in the P2(1)/c space group with Z = 8, resulting in two unique molecules in the asymmetric unit l...