Several factors contribute to organ dysfunction in septic shock patients, and once the inflammatory response has been activated, many organ systems can be adversely affected. A marked fall in systemic vascular resistance results from arterial and venous dilatation. This is accompanied by leakage of plasma into the extravascular space, leading to relative hypovolemia. The microcirculation is adv...

Sir,?In your issue for February is a letter signed " M.D. Surgeon-Major," in which, whilst charging me with " erring in ignorance," the writer shows more clearly than any words of mine could do, how much at sea many medical officers are in their ideas as to the proper use of military titles. All commissioned officers of the army have rank, honorary or substantive ; the c .esiastieal establishme...

As noted in my previous letter, it is chiefly the more senior officers who are at fault, and it is therefore to them that I specially address myself, though junior officers are by no means guiltless. Let me put before them, as briefly ami plainly as possible, a few facts of which, however they should already be fully cognisant : (1) These compound titles are practically the result of the recomm...

camera, and x-ray tube (partially hidden below table), attached to a floor-mounted parallelogram gantry to allow complex angulation; (2) lateral plane image chain attached to a ceiling-suspended gantry that can be moved into place when biplane imaging is desired; (3) and (4) television monitors for AP and lateral image chains; (5) movable radiation shield to protect operators from scatter dose ...

The Theory of Intrinsic Priors, developed by Berger and Pericchi (1996a,b), is a general method of constructing objective priors for testing and model selection when proper priors are considered for the simpler null hypotheses. When this prior distribution is improper, as is typically the case for Objective Bayesian testing, they suggest approximating the (improper) prior by a sequence of prope...

The standpoint is the station where the instrument is situated, and the forepoint is the point to which observations are being made (backsight or foresights). Figure 1, attached to this paper, shows the various distances discussed. They are described as follows: d1 is the wave path length (EDM distance corrected for atmospheric delay) d2 is the wave path chord d4 is the ellipsoidal arc length d...

The contents of pharmacist interventions, which were carried out by the ward pharmacists in their routine pharmacy service activities, were sorted and analyzed to evaluate the contributions of pharmacists. In the ward where pharmacists were stationed, there were a total of 196 cases of pharmacist intervention. The prescription was changed in 170 cases, giving a rate of prescription change of 86...

Application of biological agents targeting inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) dramatically caused a paradigm shift in the treatment of rheumatoid arthritis (RA). Infliximab, a chimeric anti-TNF-alpha monoclonal antibody, has initially been introduced to Japan in 2003 and shown to be dramatically effective in alleviating arthritis refractory to conventional tr...

ROC curves (receiver operating characteristic curves) are commonly used to portray the performance of detectors in signal-detection tasks, such as intrusion detection. This report introduces the origins of signal-detection-theory, and the underpinnings of ROC curves. It provides examples of how to construct these curves, as well as how to measure, interpret and compare them. Information about a...

Several factors contribute to organ dysfunction in septic shock patients, and once the inflammatory response has been activated, many organ systems can be adversely affected. A marked fall in systemic vascular resistance results from arterial and venous dilatation. This is accompanied by leakage of plasma into the extravascular space, leading to relative hypovolemia. The microcirculation is adv...