نتایج جستجو برای: proliferation capacity
تعداد نتایج: 452527 فیلتر نتایج به سال:
objective(s):degradation of sphingosine 1-phosphate (s1p), as a bioactive lipid, or deregulation of its production involves in tumor progression, metastasis and chemoresistance. since the tumor progression effects of s1p and its mechanism in chronic lymphoblastic leukemia and non-small cell lung cancer is not fully understood, we investigated the role and one of the mechanisms of s1p in tumor p...
background: a growing body of preclinical data indicates that statins may possess antineoplastic properties however, some studies have raised the possibility that statins may also have carcinogenic potential. methods: an air pouch model was used for angiogenesis. single or multiple applications of croton oil on the back of swiss albino mice with or without initiation by dimethylbenz(a)antherace...
abstract in this research, the effects of ba with different concentrations (0, 0.5, 1, 1.5, 2, 2.5 and 3 mg/l) in combination with iba (0, 0.01 and 0.1 mg/l) on bud growth and shoot proliferation and tdz with different concentrations (0, 1, 2, 3 and 4 mg/l) in combination with 0 and 0.5 mg/l iba on somatic embryogenesis from different parts of immature cotyledons (proximal, median and distal) w...
background: trichophyton verrucosum is a zoophilic fungus with a worldwide distribution. our aim was to investigate the proliferative effect of antigenic compounds of t. verrucosum on dermis fibro blasts and endothelial cells. methods: t. verrucosum was cultured in scc medium and was then transferred to a broth medium. surface antigens of this fungus were separated using the freeze and thaw met...
To investigate the capacity of human IL-4 to function as a B cell growth factor (BCGF), we studied its ability to promote proliferation of a selected B cell line. We show that the cell line, designated A4, proliferated in response to IL-4 in a dose-dependent manner. The A4 cells also proliferated in response to their own B cell derived growth factor (B. BCGF), suggesting autocrine-mediated grow...
The mechanism of action of the antidiabetic capacity of Momordica charantia is still under investigation. Here, we assessed phytochemical compositions, antioxidant activity, and effects of total and filtered fruit and leafy stem juices of Momordica charantia on human T cell proliferation and differentiation through quantification of Th1/Th2 cytokines. In the absence of stimulation, total fruit ...
backgrounds and aims: thyroid hormones have a crucial physiological role to maintain balance of metabolism of body. thyroid hormones have an important role in metabolism and proliferation of blood cells. thyroid gland also has a vital influence on erythropoiesis by induction of erythropoietin secretion and proliferation of erythroid progenitors. in the present study, it was tried to evaluate th...
Abstract The progression and metastatic capacity of solid tumors are strongly influenced by immune cells in the tumor microenvironment. In non–small cell lung cancer (NSCLC), accumulation anti-inflammatory tumor-associated macrophages (TAM) is associated with worse clinical outcome resistance to therapy. Here we investigated landscape NSCLC presence protumoral TAMs expressing macrophage recepto...
Alterations in the biological activity of molecules under stress conditions have not been documented as widely literature yet. This study was designed to reveal functional impacts various oxidation on a model mAb, commercial anti-VEGF IgG molecule. The responses antigen binding, cell proliferation, FcRn receptors, and C1q which rarely appear current literature, were investigated. authors report...
ERK-regulated cell proliferation requires multiple phosphorylation events catalyzed first by MEK and then by casein kinase 2 (CK2), followed by interaction with importin7 and subsequent nuclear translocation of pERK. We report that genetic manipulation of a core component of the actin filaments of cancer cells, the tropomyosin Tm5NM1, regulates the proliferation of normal cells both in vitro an...
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