Objective(s):Estrogen is a sexual hormone that has prominent effects on reproductive and non-reproductive tissues. The aim of this study is to evaluate the effects of estrogen on the proliferation and neural differentiation of human adipose derived stem cells (ADSCs) during neurogenic differentiation. Materials and Methods: Isolated human ADSCs were trans-differentiated in neural induction med...

 Introduction: Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis. New procedure such as sound wave especially low intensity ultrasound (LIUS) can be effective on increasing the number of cells. In this study, the effect of LIUS stimulation on mouse SSCs proliferation and colonization was investigated. Methods: Isolated SSCs from neonatal mice were cultured in DMEM cultur...

Transforming growth factor beta (TGF-b) is a mediator released by nearly all cell types. It has suppression activity on the immune system, but exactly how this effect is carried out is not clear. Previous experiments showed that IgG interacts with or carriers active TGF-b, that could suppresses cytotoxic T-cell responses to an immunogenic tumor in mice. Since T cell receptor (TCR) has structura...

in order to micropropagate of four vigorous rootstocks of pear, including pyrus betulifolia, konjuni, dargazi and gh1, effects of basic plant culture media (ms, ql and modified ql), cytokinins and auxins on productivity, proliferation and rooting were studied in seed and plant improvement institute, karaj. the highest amount of productivity for all rootstocks was observed in ql medium. among pe...

The proliferation of hepatocellular carcinoma (HCC) cells is one of the leading causes of liver cancer mortality in humans. The inhibiting effects of matrine on HCC cell proliferation have been studied, but the mechanism of that inhibition has not been fully elucidated. Since, apoptosis plays an important role in HCC cell proliferation. We examined the apoptosis-inducing effect of matrine on tu...