Model-Integrated Computing, specifically Model-Integrated Program Synthesis (MIPS) environments that include visual model building, constraint management, and automatic program synthesis components, are well suited for the design and implementation of complex computerbased systems. However, building such an environment from scratch for each new domain can be cost-prohibitive. This paper present...

Cascaded channels are very often used in practice. They become necessary because some waves like microwave links and the electromagnetic wave do not follow the curvature of the earth, because the shrinking suffered by the signal becomes prohibitive when the distance becomes large. In such conditions the designer forced to break up the whole channel in to a cascade of channels. It is also called...

Tuberculosis (TB) is a worldwide disease, and nosocomial transmission is known to occur. Authoritative preventive guidelines such as the one developed by the Centers for Disease Control have been published, but the expenses for implementing them can be prohibitive. Each country needs to develop its own protocol to prevent nosocomial transmission of TB. This article describes the key elements of...

Natural gradient is a gradient descent technique which uses the inverse of the covariance matrix of the gradient. Using the centrallimit theorem, we prove that it yields the direction that minimizes the probability of overfitting. However, its prohibitive computational cost makes it impractical for online training. Here, we present a new online version of the natural gradient which we coin TONG...

The nonlinear selfdual variational principle established in the first part of this paper [8] – though good enough to be readily applicable in many stationary nonlinear partial differential equations – did not however cover the case of nonlinear evolutions such as the Navier-Stokes equations. One of the reasons is the prohibitive coercivity condition that is not satisfied by the corresponding se...

We investigate the problem of determining a compact underspecified semantical representation for sentences that may be highly ambiguous. Due to combinatorial explosion, the naive method of building semantics for the different syntactic readings independently is prohibitive. We present a method that takes as input a syntactic parse forest with associated constraintbased semantic construction rul...

This paper presents some preliminary validation study results pertaining to our ongoing attempts to develop a noninvasive scoliosis and other spine disorder automated diagnostic solution implemented using commodity sensors only, thus limiting its overall cost, but still achieving adequate precision. The cost of many such commercial solutions is prohibitive to have them acquired and used by stud...

Background/Introduction Implantation of transcatheter aortic bioprosthesis has become a procedure with increasingly relevance in medical practice for the treatment of aortic stenosis, especially in patients with high or prohibitive surgical risk for traditional surgery. The presence of mitral regurgitation (MR) may be associated with increased morbidity and mortality, however, some studies have...

It would appear as if the author was unaware of Besredka's work on sensitized living vaccines when he writes :?" The use of living bacteria, if they could be so attenuated as to be harmless, would accomplish it (raising of opsonic power), but would be manifestly objectionable and subject to almost prohibitive limitations." In the chapter on " The Process of. Healing" regeneration of bone is som...

Numerical simulations are important for many systems. In particular, various standard computer programs have been developed for solving the quantum Schrödinger equations. However, the accuracy of these calculations is limited by computer capabilities. In this work, an iterative method is introduced to enhance the accuracy of these numerical calculations, which is otherwise prohibitive by conven...