نتایج جستجو برای: progressive retinal atrophy

تعداد نتایج: 225473  

Journal: :Veterinary pathology 1995
R Bildfell C Matwichuk S Mitchell P Ward

Neuronal ceroid-lipofuscinosis was diagnosed in a young adult domestic short-haired cat euthanatized because of severe progressive neurologic disease. Clinical signs included blindness, seizures, and decreased mentation. An autofluorescent pigment, identified as ceroid-lipofuscin by electron microscopy and staining properties, was found within neurons of the central and peripheral nervous syste...

Journal: :Annals of Indian Academy of Neurology 2015

Journal: :Contemporary Clinical Dentistry 2012

Journal: :Proceedings of the Royal Society of Medicine 1931

Journal: :British Journal of Ophthalmology 2006

Journal: :Investigative ophthalmology & visual science 2018
Sarah Thiele Maximilian Pfau Petra P Larsen Monika Fleckenstein Frank G Holz Steffen Schmitz-Valckenberg

Purpose To evaluate the development of central atrophy in eyes with age-related macular degeneration (AMD). Methods Six-year longitudinal multimodal retinal imaging data (MODIAMD study) from 98 eyes of 98 subjects with non-late-stage AMD in the study eye at baseline were analyzed for the presence of central atrophy at each annual follow-up visit. Development, manifestation, and further progre...

Journal: :Investigative ophthalmology & visual science 2017
Einar Stefánsson Olof Birna Olafsdottir Anna Bryndis Einarsdottir Thorunn Scheving Eliasdottir Thor Eysteinsson Wouter Vehmeijer Evelien Vandewalle Toke Bek Sveinn Hakon Hardarson

Purpose Biomarkers for several eye and brain diseases are reviewed, where retinal oximetry may help confirm diagnosis or measure severity of disease. These include diabetic retinopathy, central retinal vein occlusion (CRVO), retinitis pigmentosa, glaucoma, and Alzheimer's disease. Methods Retinal oximetry is based on spectrophotometric fundus imaging and measures oxygen saturation in retinal ...

Journal: :international journal of pediatrics 0
farah ashrafzadeh professor of pediatric neurology ward, faculty of medicine, mashhad university of medical sciences, mashhad, iran. ariane sadr-nabavi assistant professor of human genetic, faculty of medicine, mashhad university of medical sciences, mashhad, iran. nazanin asadian students research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran. javad akhondian professor of pediatric neurology ward, faculty of medicine, mashhad university of medical sciences, mashhad, iran. mehran beiraghi toosi assistant professor of pediatric neurology ward, faculty of medicine, mashhad university of medical sciences, mashhad, iran.

spinal muscular atrophy (sma) is a genetic disorder which affect nervous system and is characterized with progressive distal motor neuron weakness. the survival motor neuron (smn) protein level reduces in patients with sma. two different genes code survival motor neuron protein in human genome. skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory fa...

Journal: :Arquivos brasileiros de oftalmologia 2012
Rodrigo Fabri Berbel Paulo Igor Rauen Raphael Frangiote Pallone Antônio Marcelo Barbante Casella

To report a case of gyrate atrophy of the choroid and retina associated with retinal detachment. Hyperornithinemia confirmed the diagnosis of gyrate atrophy. Pars plana vitrectomy with silicone oil infusion was performed with good anatomical results, despite the persistence of low visual acuity. Retinal detachment is a rare complication of gyrate atrophy and can be managed with pars plana vitre...

Journal: :Nature communications 2016
Bethany A Kerr Xiaoxia Z West Young-Woong Kim Yongzhong Zhao Miroslava Tischenko Rebecca M Cull Timothy W Phares Xiao-Ding Peng Jeremiah Bernier-Latmani Tatiana V Petrova Ralf H Adams Nissim Hay Sathyamangla V Naga Prasad Tatiana V Byzova

The signalling pathways operational in quiescent, post-development vasculature remain enigmatic. Here we show that unlike neovascularization, endothelial Akt signalling in established vasculature is crucial not for endothelial cell (EC) survival, but for sustained interactions with pericytes and vascular smooth muscle cells (VSMCs) regulating vascular stability and function. Inducible endotheli...

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