Multiple system atrophy is a progressive neurodegenerative disorder that is characterized by autonomic failure, cerebellar ataxia and parkinsonism syndrome in various combinations. In spite of the presence of well-established clinical criteria for multiple system atrophy, ante-mortem diagnosis is difficult. In our case report, we present a 78-year-old female patient who presented with early pro...

Patients with corticobasal degeneration can present with several different clinical syndromes, making ante-mortem diagnosis a challenge. Corticobasal syndrome is the clinical phenotype originally described for corticobasal degeneration, characterized by asymmetric rigidity and apraxia, cortical sensory deficits, dystonia and myoclonus. Some patients do not develop these features, but instead ha...

A 70-year-old woman presented with a 2-year history of progressive difficulty in walking with frequent falls. Neurologic examination showed postural instability with backward falls, vertical supranuclear gaze palsy with normal vestibular-ocular reflex, rigidity, and pyramidal signs in the right limbs. There was no clinical response to levodopa. Laboratory serologic tests had normal results. MRI...

概 要PSP排 泄 試験に含 まれ る腎血流 以外 の副次 的な情報を解 析 し,PSPの 腎排 泄に お よぼす各 種 因子 の影響 を定量 的に把握 す るため,PSP排 泄 のkineticsの模擬 を試 みた.ま ず動 物実 験 の結 果, PSPは 体内で二 相分布を とる ことが判 明 した ので,こ れに基づ き数学 モデルを作成 し,電 子計算機 に よ りsimulationを 行 なつた ところ,そ の応答曲 線 は動物実験 に よる実 測値 とよ く一 致 し,モ デル の 妥 当性を裏づ け る成績を得 た.そ こでモデル の医学 的意義 を検 討 した結果,PSP分 布 の第1相 は循 環血漿,第2相 は肝腸系 と推定 され,ま た移行係 数k1, k2, k3は それぞれ腎 か らの排泄 能,肝 の異物 排 泄 能,腸 管吸 収を意味す るもの と考 え ...

We compared image restoration methods [Richardson-Lucy (RL), Wiener, and Next-image] with measured "scatter" point-spread-functions, for removing subsurface fluorescence from section-and-image cryo-image volumes. All methods removed haze, delineated single cells from clusters, and improved visualization, but RL best represented structures. Contrast-to-noise and contrast-to-background improvemen...

A scientific model need not be a passive and static descriptor of its subject. If the subject is affected by the model, the model must be updated to explain its affected subject. In this study, two models regarding the dynamics of model aware systems are presented. The first explores the behavior of "prediction seeking" (PSP) and "prediction avoiding" (PSP) populations under the influence of a ...

The aim of this study is to fill a gap in intelligence research by presenting data for the average IQ in Morocco and for a comparable sample in Spain. Adult samples were administered the Raven Standard Progressive Matrices (SPM) (Raven, Court, & Raven, 2001) and scored for the total test and for the three sub-factors of gestalt continuation, verbal-analytical reasoning and visuospatial ability ...

Chinese-American and Anglo-American school children were compared on a nonverbal test of intelligence (Raven's Progressive Matrices) and on twelve chronometric variables which measure the speed with which basic information processes (e.g. stimulus apprehension, decision, and discrimination) can be carried out. All of these tasks are correlated with psychometric intelligence. The two groups diff...

OBJECTIVE The authors present the case of a dumbbell-shaped schwannoma of the upper cervical spine involving the ventral rami of C-2 sensory root and rising through the foramen magnum up to the pontobulbar junction. The 27-year-old male patient complaining of hoarseness, imbalance and experiencing cervical pain and cervical muscle contractions for 2 months was admitted to the hospital. The cerv...