BACKGROUND Loss of function mutations in the DJ-1 gene have been linked to recessively inherited forms of Parkinsonism. Mitochondrial dysfunction and increased oxidative stress are thought to be key events in the pathogenesis of Parkinson's disease. Although it has been reported that DJ-1 serves as scavenger for reactive oxidative species (ROS) by oxidation on its cysteine residues, how loss of...

Abstract Capillary dominated flow or imbibition—whether spontaneous forced—is an important physical phenomena in understanding the behavior of naturally fractured water-driven reservoirs (NFR’s). When water flows through fractures, it imbibes into matrix and pushes oil out pores due to difference capillary pressure. In this paper, we focus on modeling quantifying recovered from NFR’s imbibition...

Abstract The thermoconvective instability of the parallel vertical flow in a fluid saturated porous layer bounded by open boundaries is studied. are assumed to be kept at constant uniform pressure while their temperatures and different, thus forcing horizontal temperature gradient across layer. anisotropic permeability accounted for assuming principal axes oriented along directions perpendicula...

The permeability of the preform composite materials used in liquid molding processes such as resin transfer molding and structural reaction injection molding is a complex function of weave pattern and packing characteristics. The development of tools for predicting permeability as a function of these parameters is of great industrial importance. Such capability would speed process design and op...

permeability is a property of porous medium that quantifies rock capacity to transmit fluids. frequently, core based permeability data are not available either because of the borehole conditions or due to the high cost of coring. for these reasons, over the years attempts have been made to estimate permeability by alternative ways. permeability is an elusive parameter in hydrocarbon reservoirs ...

more than half of all hydrocarbon reservoirs are naturally fractured reservoirs (nfrs), in which production forecasting is a complicated function of fluid flow in a fracture-matrix system. modelling of fluid flow in nfrs is challenging due to formation heterogeneity and anisotropy. stress sensitivity and depletion effect on already-complex reservoir permeability add to the sophistication. horiz...

new edible composite films formed from salep (orchis mascula) and 10%, 20%, and 30% (w/w) oleic acid were prepared by emulsification with the aim of improving the water vapor barrier and mechanical properties of the film. as oleic acid concentration increased up to 30% (w/w), oxygen permeability (27%), elongation at break (86%) and thickness (2%) of salep films increased significantly and the t...

The central Apennines are a fold-thrust belt currently affected by post-orogenic extensional seismicity. To constrain the influence that inherited thrust-related structures exert on present seismic behavior of belt, we provide high-resolution structural and hydraulic characterization one most external exposed thrust fault systems Apennines, Sibillini Mts. Thrust Front (STF). We integrate mappin...