OBJECTIVE The role of inorganic phosphate in the pathogenesis of vascular calcification (VC) has been studied extensively in recent years. Phosphonoformic acid (PFA), an inhibitor of type II Pi transporters, has been traditionally used to study the involvement of Pi transport in VC, because PFA also prevents calcium deposition in vitro. However, aortic vascular smooth muscle cells (VSMCs) only ...

We investigated whether the inclusion of the PFA-100 in the preoperative screening of neurosurgical patients might reduce perioperative bleeding complications. Patients with intracranial space-occupying lesions who were scheduled for neurosurgery underwent routine preoperative PFA-100 testing. In case of an abnormal PFA test, patients received prophylactic treatment with desmopressin. 93 consec...

In these notes we will present an exposition of the Proper Forcing Axiom (PFA). We will first discuss examples of the consequences of PFA. We will then present two proper partial orders which are used to force two combinatorial principles which follow from PFA: The P-Ideal Dichotomy (PID) and Todorcevic’s formulation of the Open Coloring Axiom. On one hand, these posets and the proofs of their ...

When applied topically, trisodium phosphonoformate (PFA) displayed activity against established cutaneous herpesvirus infections in guinea pigs similar to that exhibited by the closely related phosphonoacetic acid (PAA); however, unlike PAA, PFA was not locally skin irritating. The therapeutic benefits of topical application of PFA were clearly evident when application was delayed for 48 h afte...

The ability to conduct valid assessment of teachers’ attitude towards teaching of a technical course is important as teachers’ attitude influences the quality of teaching and students’ learning experience. This paper focuses on the development and validation of an instrument for assessing technical teachers’ attitudes towards teaching engineering drawing. The study used a developmental research...

this paper aims at determining isfahan provincial industries orientation as well as relating the comparative advantage indexes and their changes with the province’s industrial characteristics. therefore, applying “factor analysis”, “principal components analysis” and “numerical taxonomy analysis” methods, the paper calculates the determining indexes of the province’s industrial development and ...

Electronic Health Record (EHR) phenotyping utilizes patient data captured through normal medical practice, to identify features that may represent computational medical phenotypes. These features may be used to identify at-risk patients and improve prediction of patient morbidity and mortality. We present a novel deep multi-modality architecture for EHR analysis (applicable to joint analysis of...

The PFA-100 is an in vitro system for measurement of platelet function in whole blood. To establish reference intervals in the Korean population, we investigated the relationships between PFA-100 closure times and gender, ABO blood group, citrate concentration, and time of blood collection in 120 well-characterized healthy Korean adults. Gender did not affect closure time values. Blood group O ...

Several methods are available for computing the location of the point of force application (PFA) in manual wheelchair propulsion using kinetic data. We compared five different techniques for computing the PFA location in analysis of data from five wheelchair users propelling their own wheelchairs using their normal propulsion style. The effects of the assumptions used in the calculations on the...

the species of dioscorea (yam) are regarded as a staple food crop for millions of people in the tropical and subtropical regions of the world. it is regarded as an important food crop next to cereals and grains due to high yield storage of carbohydrates. economically, only few species are recognized for cultivation from agricultural point of view, in spite of its large species diversity. the sp...