Myasthenia gravis (MG) is an autoimmune disorder characterized by autoantibodies against acetylcholine receptors. MG is generally an isolated disorder but may occur concomitantly with other autoimmune diseases. We describe an eighteen-year-old girl with MG who was admitted to our clinic with secondary amenorrhea and diagnosed as autoimmune oophoritis. Since her myasthenic symptoms did not resol...

PURPOSE A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian cancer risk in patients from hereditary breast and ovarian families (HBOC), and with the risk of premenopausal triple negative breast cancer, we evaluated the association of t...

Ovarian pregnancy is a rare event occurring in 1-3% of all ectopic pregnancies. Increased reporting might be due to the wider use of intra-uterine devices, ovulatory drugs and assisted reproductive techniques. Though ovarian pregnancy has a distinct pathology, it can be a source of clinical and intraoperative diagnostic difficulty. We report two cases of ovarian pregnancy - one primary and one ...

Background: Immaturity of the ovarian follicles results in an infertility citation called Premature Ovarian Failure (POF), affecting approximately 1% of women under the age of 40. Women with this disorder go through early menopause and have high levels of gonadotropin hormones (FSH & LH). Diminished Ovarian Reserve (DOR) is another infertility disorder in which women’s ovaries have the ability ...

Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder commonly found in females their reproductive ages and associated with hirsutism, obesity, menstrual irregularities, insulin resistance. PCOS management includes the medicinal approach increased incidence of PCOS, herbal has been increasing which flaxseeds flaxseed oil but to further explore benefits, more researches are be conducted af...

background: we examined epidemiological aspects of dynamic changes in incidence of ovarian cancer in women of kazakh and russian nationalities in kazakhstan. methods: the material of investigation was primary data on registered patients with malignant ovarian tumors in the whole country. the study was conducted during the period of 1999-2009. evaluation of changes in ovarian cancer incidence in...

Approximately 6-7% of all adnexal masses found during physical examination are actually metastatic ovarian tumors, which often masquerades as the primary ovarian tumor. The circumstances leading to the discovery of these metastatic lesions depends on the site of the primary tumor. The ovaries may be only slightly enlarged or measure 10 cm or more. Ovarian metastases are bilateral in approximate...

BACKGROUND Ovarian cancer remains a leading cause of death in women and development of new therapies is essential. Second mitochondria derived activator of caspase (SMAC) has been described to sensitize for apoptosis. We have explored the pro-apoptotic activity of LBW242, a mimic of SMAC/DIABLO, on ovarian cancer cell lines (A2780 cells and its chemoresistant derivative A2780/ADR, SKOV3 and HEY...

Polycystic Ovarian Syndrome (PCOS) is endocrine and gynecological disorder that affects women of reproductive age. This a case report patient with PCOS who was misdiagnosed presented several symptoms. emphasizes the need for holistic healthcare approach to treat underlying organ dysfunction in PCOS. It highlights interconnectedness between dysfunction. examines chronic inflammatory state, risk ...