نتایج جستجو برای: pressure regulation

تعداد نتایج: 944149  

2001
Nicolás Porteiro Johan Eyckmans Paula González

We study a problem of adverse selection in the context of environmental regulation, where the Þrm may suffer from a certain degree of ignorance about its own type. In this framework we analyze the impact on the regulatory process of the presence of informed third-parties. We study and compare the role of environmentalists and of unbiased experts. Our analysis allows us to support the spirit of ...

2000
L. Gabriel Navar L. Lee Hamm

Despite extensive animal and clinical experimentation, the mechanisms responsible for the normal regulation of arterial pressure and development of essential or primary hypertension remain unclear. One basic concept was championed by Guyton and other authors [1–4]: the long-term regulation of arterial pressure is intimately linked to the ability of the kidneys to excrete sufficient sodium chlor...

2010
María Castañeda-Bueno Gerardo Gamba

Arterial hypertension is one of the most important health problems in industrialized cities. Blood pressure levels are influenced by renal salt handling and salt reabsorption in the kidney. In this Closeup, Castañeda-Bueno and Gamba discuss the work from Alessi and coworkers on the in vivo roles of the SPAK kinase in defining blood pressure levels.

2005
A. Guillermo Scicli O. A. Carretero

During the last decade, the actions of central nervous system peptides on blood pressure and volume homeostasis have been the subject of intense investigation. There is evidence that central mechanisms of cardiovascular control could be modulated by brain peptides. Kinins are biologically active peptides released from kininogen by either glandular or plasma kallikrein. Kinins in the central ner...

2012
Ivan Sekaj Josef Zicha Michal Behuliak Peter Bališ Miroslava Majzúnová Iveta Bernátová

A bio-cybernetical model of blood pressure regulation in rats is presented. Timeresponses of blood pressure after administration of selected drugs are identified and linear dynamic models of the cardiovascular system using genetic algorithms are calculated in the Matlab environment. The three major regulation systems – sympathetic nervous system, renin-angiotensin-aldosterone system and LArgini...

Journal: :Current opinion in pharmacology 2015
Antoine Tarjus Cristian Amador Luis Michea Frédéric Jaisser

The mineralocorticoid receptor (MR) is a major regulator of blood pressure by modulating sodium balance and blood volume in the distal nephron. The discovery of MR expression in both endothelial and vascular smooth muscle cells a decade ago raised questions about its role in the vascular wall and its involvement in blood pressure regulation. In vitro and in vivo pharmacological studies have sho...

Journal: :Clinical science and molecular medicine. Supplement 1975
A Philippu

Abolfazl Khajavirad, Amir Baniasad Mahmoud Ghavi Mahmoud Hosseini, Mohammad Naser Shafei, Saeed Aminzadah

Objective: Rosa damascena mill L. (R. damascena) is a well-known plant with fragrant effects. Several therapeutic effects of this plant on respiratory, gastrointestinal and nervous systems have been reported. It is also suggested to have beneficial effect on cardiovascular system especially blood pressure regulation. The present study was carried out to evaluate acute cardiovascular effect of h...

امیری, ایرج , بهزادی, ژیلا , زارع اکباتانی, رفعت , صریحی, عبدالرحمان , ملکوتی, سیّد منصور , کورش آرامی, معصومه ,

Background: The role of nucleus tractus solitarius in cardiovascular system regulation is controversial. On the other hand, study on the problem of hypertension in diabetic animals is the subject of many research programs. The aim of the present study was to determine wheather inactivation of nucleus can affect blood pressure in diabetic rats. Methods: To this end , stereptosotocin-induc...

Journal: :Hypertension 2010
Maciej Tomaszewski Radoslaw Debiec Peter S Braund Christopher P Nelson Robert Hardwick Paraskevi Christofidou Matthew Denniff Veryan Codd Suzanne Rafelt Pim van der Harst Dawn Waterworth Kijoung Song Peter Vollenweider Gerard Waeber Ewa Zukowska-Szczechowska Paul R Burton Vincent Mooser Fadi J Charchar John R Thompson Martin D Tobin Nilesh J Samani

Genetic determinants of blood pressure are poorly defined. We undertook a large-scale, gene-centric analysis to identify loci and pathways associated with ambulatory systolic and diastolic blood pressure. We measured 24-hour ambulatory blood pressure in 2020 individuals from 520 white European nuclear families (the Genetic Regulation of Arterial Pressure of Humans in the Community Study) and ge...

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