BACKGROUND We examined the association of maternal obesity with risk of stillbirth, focusing on whether the pattern of results varied by gestational age or maternal race-ethnicity or parity. METHODS Analyses included 4,012 stillbirths and 1,121,234 liveborn infants delivered in California from 2007-2010. We excluded stillbirths due to congenital anomalies, women with hypertensive disorders or...

CONTEXT In diabetic pregnancy, neonatal hypoglycemia (NH) is usually attributed to insufficient regulation of maternal glycemic control. Recent data suggest that maternal body mass index (BMI) could have an influence. OBJECTIVE Our objective was to determine whether an association exists between maternal prepregnancy BMI category and occurrence of NH among infants born to women with gestation...

BACKGROUND To evaluate the association between rate of gestational weight gain and preterm birth varying prepregnancy body mass indices and trimester. METHODS Data from Maternal and Newborn's Health Monitoring System on 17475 pregnant women who delivered live singletons at ≥ 28 weeks of gestation between October 2013 and September 2014 from 12 districts/counties of 6 provinces in China and st...

OBJECTIVE Birth weight has been associated with the risk of type 2 diabetes in several studies. We investigated whether prenatal influences on birth weight (gestational age, parity, preeclampsia, prepregnancy BMI, smoking during pregnancy, and socioeconomic position [SEP]) were associated with glucose metabolism in midlife and the role of birth weight for gestational age (BGA) and adult adiposi...

BACKGROUND Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate pathway genes could modify this association or directly influence CBT risk. METHODS Associations between risk of CBT and folate pathway polymorphisms were investigated in a population-based case-control study in Australia (2005...

BACKGROUND Cardiovascular events (stroke or myocardial infarction) are often associated with poorer prognosis in younger, compared with older individuals. We examined the associations between prepregnancy obesity and the risks of myocardial infarction and stroke in young, healthy women. METHODS AND RESULTS All Danish women giving birth during 2004-2009 without a history of renal disease or ca...

BACKGROUND Excessive weight gain during pregnancy is a risk factor for postpartum weight retention and future weight gain and obesity. Whether a behavioral intervention in pregnancy can reduce long-term weight retention is unknown. OBJECTIVE This randomized trial tested whether a low-intensity behavioral intervention to prevent excessive gestational weight gain could increase the proportion o...

Background: To determine the relationship between prepregnancy obesity and increasing risk of cesarean section (CS). Materials and Methods: The population studied included 887 women with live births after 37 weeks gestation in Shahid Sedoughi hospital between April 1, 2008, and April 1, 2009. Women who were obese before pregnancy were comparing with nonobese women with regard to mode of deliver...