The molybdenum nitride complex [(Ph(3)SiO)(3)Mo[triple bond]N] (10), which can be conveniently prepared in situ from readily available [(Me(3)SiO)(2)((Me(3)Si)(2)N)Mo[triple bond]N] (9) and Ph(3)SiOH, and the pyridine adduct of 10, [(pyridine)(Ph(3)SiO)(3)Mo[triple bond]N] (11), exhibit excellent catalytic activity in alkyne metathesis reactions of all kinds. Adduct 11 is sufficiently stable to...

A convergent one-step transformation of tetrahydropyranyl (THP) ethers is described. According to our earlier experiments, indium(III) triflate has proven to be an efficient catalyst for the transformation of THP ethers into their corresponding acetates. In further intensive work, we have developed a useful transforming reaction of THP ethers using various anhydride moieties. Indium(III) trifla...

Thirty-six halogenated Me Et ethers have been synthesized for evaluation as volatile anesthetics. Eleven of the ethers were too unstable to test, and, of the remaining 25, 13 had promising anesthetic properties in mice and are suitable for study in larger animals. Those ethers having one H with at least 2 halogens other than F or 2 or more H with at least one Br or Cl were the best anesthetics.

Transition-metal-catalyzed cycloisomerization and cyclization reactions of enynes have emerged as powerful methods for the construction of heteroand carbocyclic compounds.1 More recently, enantioselective cycloisomerization of 1,6and 1,7-enynes has been employed in the preparation of enantioenriched 1,4-diene containing structures.2-4 Despite its potential utility, the related enantioselective ...

A domino reaction has been developed for the synthesis of oxygen bridged bicyclic ethers through the coupling of 4-(2-hydroxyethyl)cyclohex-3-enols with aldehydes in the presence of 10 mol% of molecular iodine in dichloromethane at 25 °C. This method is highly diastereoselective affording the corresponding bicyclic ethers, i.e. octahydro-4a,7-epoxyisochromenes in good yields with high selectivi...

The "chlorination/fluorination" technique for aliphatic trifluoromethyl ether synthesis was investigated and a range of products with various functional groups was prepared. The results were compared with oxidative desulfurization-fluorination of xanthates with the same structure.

To probe the influence of structural variation within dibenzo-16crown-5-oxyacetic acids upon the selectivity of alkali metal cation separations by solvent extraction and liquid membrane transport processes, studies have now been conducted in homogeneous solution by NMR spectroscopy and titration calorimetry and in the solid state. Condensation polymerization of such proton-ionizable lariat ethe...

Gold-catalyzed intermolecular couplings of sulfonylacetylenes with allyl ethers are reported. A cooperative polarization of alkynes both by a gold catalyst and a sulfonyl substituent resulted in an efficient intermolecular tandem carboalkoxylation. Reactions of linear allyl ethers are consistent with the [3,3]-sigmatropic rearrangement mechanism, while those of branched allyl ethers provided [3...