Background and Objectives: The most effective treatment of infertility is in vitro fertilization (IVF). IVF with Preimplantation Genetic Testing (PGT) allows to identify embryos a genetic abnormality associated specific medical disorder select the optimal for transfer. PGT divided into structural rearrangement testing (PGT-SR), monogenetic (PGT-M), aneuploidy (PGT-A). This study mostly analyzes...

A broad range of testing modalities for fetal genetic disease has been established. These include carrier screening for single-gene mutations, first-trimester and second-trimester screening for chromosome abnormalities and open neural-tube defects, prenatal diagnosis by means of chorionic villus sampling and amniocentesis, and preimplantation genetic diagnosis. Reproductive decisions before and...

1 E mbryonic research and genetic testing continue to raise concerns. 1 With controversy comes debate and, sometimes, distortion of facts through the use of loaded terms and concepts that call to mind both historical events and science fiction. Achieving greater public understanding of genetic diagnosis of embryos, known generally as preimplantation genetic diagnosis (see definitions of terms i...