The Fox-1 RNA recognition motif (RRM) domain is an important member of the RRM protein family. We report a 1.8 Å X-ray structure of the free Fox-1 containing six distinct monomers. We use this and the nuclear magnetic resonance (NMR) structure of the Fox-1 protein/RNA complex for molecular dynamics (MD) analyses of the structured hydration. The individual monomers of the X-ray structure show di...

Contrast-induced nephropathy (CIN) is a complex syndrome of acute kidney injury that follows exposure to intravascular contrast media. Although a series of preventive measures have been developed, CIN remains a major challenge encountered in elderly patients by interventional cardiologists. No data are currently available concerning the potential effects of the combined use of hydration and alp...

PURPOSE To evaluate the effects of stromal hydration on clear corneal incision (CCI) architecture immediately after surgery using anterior segment optical coherence tomography (AS-OCT). SETTING Department of Ophthalmology, Royal Berkshire Hospital, Reading, United Kingdom. METHODS Clear corneal incisions in adult eyes were examined using a Visante AS-OCT imaging system within 1 hour of surg...

Objective:To study the effects of oral and intravenous maternal hydration in third trimester idiopathic or isolated oligohydramnios, and to determine the duration of actions. Design: Prospective clinical study. Setting:OB/GYN department, Benha Teaching Hospital, Benha, Egypt.; Patient(s):34 pregnant patients, about 35 weeks gestation, with idiopathic oligohydramnios. Intervention(s):acute oral ...

Transport of liquids by pervaporation takes place by a solution-diffusion mechanism. In order to investigate the “solution part” of this transport model, preferential sorption has been compared with preferential permeability. Sorption equilibria and pervaporation experiments for the systems water-ethanol-cellulose acetate, water-ethanol-polyacrylonitrile and water-ethanol-polysulfone have been ...

Additives are commonly used to tune macromolecular conformational transitions. Among additives, trehalose is an excellent bioprotectant and among responsive polymers, PNIPAM the most studied material. Nevertheless, their interaction mechanism so far has only been hinted without direct investigation, and, crucially, never elucidated in comparison proteins. Detailed insights would help understand...

BACKGROUND Inadequate hydration in the elderly is associated with increased morbidity and mortality. However, few studies have addressed the knowledge of elderly individuals regarding hydration in health and disease. Gaps in health literacy have been identified as a critical component in health maintenance, and promoting health literacy should improve outcomes related to hydration associated il...

Supersulfated cement, with higher waste utilization and less cement clinker is the inevitable trend of the development of green material in the rapid developed industrial era. For the wide use of supersulfated cement in our country, the hydration heat is analyzed in this paper. The hydration kinetic parameters are obtained from the hydration heat and hydration heat rate curves measured by the i...

BACKGROUND AND OBJECTIVES During pregnancy, the body exhibits dynamic changes in fluid composition. More than 50%of women experience nausea and vomiting during the first trimester. Studies of hydration status in pregnant women are limited, and not in tropical countries, like in Indonesia. The objective of this study was to investigate the hydration status and appropriate biomarkers for determin...

INTRODUCTION There is scarce and inconsistent information about gender-related differences in the hydration of sports persons, as well as about the effects of hydration on performance, especially during indoor sports. OBJECTIVE To determine the physiological differences between genders during in indoor physical exercise, with and without hydration. METHODS 21 spinning sportspeople (12 men a...