BACKGROUND To investigate thyroid function in preeclamptic patients in comparison with normal pregnant women. METHODS In this analytical cross-sectional study free Thyroxine (T4), and Thyroid Stimulating Hormone (TSH) levels were measured in 100 preeclamptic patients and were compared with Free T4 and TSH levels in 101 normal pregnant women in their third trimester of pregnancy. Patients with...

The purpose of this study was to investigate the expression of estradiol and estrogen receptor α (ESRα) in severe preeclamptic (sPE) pregnancies compared with normal pregnancies. Sera and placentas were obtained from i) patients with sPE (n=25) and ii) a normal control group (n=25) who underwent elective Cesarean deliveries. Estradiol expression w...

In this prospective cohort study, we compared the incidence and severity of spinal anesthesia (SA) associated hypotension in preeclamptics (n=25) versus healthy parturients (n=25) undergoing cesarean delivery. After proper preloading, SA was administered with 0.75% hyperbaric bupivacaine. Blood pressure (BP) was recorded before performing SA (baseline BP), and then after SA, every 2 minutes for...

Title:Birth after preeclamptic pregnancies: association with allergic sensitization and allergic rhinoconjunctivitis in adolescence. A historically matched cohort study.

Background The aim of this study was to evaluate copper status in women with preeclampsia. MaterialsAndMethods Sixty preeclamptic, sixty normotensive pregnant and sixty healthy nonpregnant women were enrolled in a cross sectional study. The 24-hour urine copper was compared among the women. Results There was significant difference in the copper concentration of 24-hour urine among the three gro...

Less nitric oxide (NO)-dependent vasodilation and excess formation of reactive oxygen species could explain poor placenta perfusion in preeclampsia, but the pathways involved are unknown. We tested the hypothesis that reduced NO activity and increased oxidative stress in preeclamptic placenta is related to a low bioavailability of l-arginine. Placental endothelial NO synthase (ecNOS) expression...

Endothelial cell activation is important in the pathogenesis of preeclampsia; however, the nature of the activation is unknown. We investigated 22 patients with preeclampsia. 29 normotensive pregnancies, and 18 nonpregnant women to test the hypothesis that serum from preeclamptic patients induces expression of intercellular adhesion molecule-1 (ICAM-1) and vascular adhesion molecule-1 (VCAM-1) ...

Preeclampsia is the leading cause of morbidity and mortality in pregnancy. Although the etiology of preeclampsia is still unclear, it is believed to involve rejection of the fetus, possibly due to an imbalance between regulatory (Treg) and effector T cells. To test this, we compared the frequencies of circulating CD4(+) T cells expressing Foxp3, IFN-gamma, IL-10, or IL-17 at the end of the thir...

BACKGROUND Recent investigations have demonstrated a positive association between periodontitis and pregnancy complications. The purpose of this study was to determine the effect of periodontitis and the subgingival microbial composition on preeclampsia. METHODS A case-control study was carried out in Cali, Colombia that included 130 preeclamptic and 243 non-preeclamptic women between 26 to 3...

The aim of this study was to assess Serum Calcium (SCa) levels in the women with preeclamptic and normotensive pregnancies and to estimate its levels in cord blood with a view to relate the levels in pregnant mothers with their new born babies. This observational study was carried out in the Department of Biochemistry in PGIMS, Rohtak from February 2015 to July 2015. Thirty apparently normal pr...