It is widely accepted that modern humans conform to Bergmann's rule, which holds that body size in endothermic species will increase as temperature decreases. However, there are reasons to question the reliability of the findings on which this consensus is based. One of these is that the main studies that have reported that modern humans conform to Bergmann's rule have employed samples that con...

An operon is a fundamental unit of transcription and contains specific functional genes for the construction and regulation of networks at the entire genome level. The correct prediction of operons is vital for understanding gene regulations and functions in newly sequenced genomes. As experimental methods for operon detection tend to be nontrivial and time consuming, various methods for operon...

We have carried out a systematic analysis of the contribution of a set of selected features that include three new features to the accuracy of operon prediction. Our analyses have led to a number of new insights about operon prediction, including that (i) different features have different levels of discerning power when used on adjacent gene pairs with different ranges of intergenic distance, (...

We will trace today the history of the prediction paradox from Professor Oskar Morgenstern's first rigorous formulation up to the present. The prediction paradox is defined for that situation where an infinite series of reciprocally conjectural reactions and counter-reactions between two or more actors occurs. These reactions occur when the calculation of the outcomes of one agent's future beha...

Room acoustic indicators of intelligibility have focused on the effects of temporal smearing of speech by reverberation and masking by diffuse ambient noise. In the presence of a discrete noise source, these indicators neglect the binaural listener's ability to separate target speech from noise. Lavandier and Culling [(2010). J. Acoust. Soc. Am. 127, 387-399] proposed a model that incorporates ...

Folds are the basic building blocks of protein structures. Understanding the emergence of novel protein folds is an important step towards understanding the rules governing the evolution of protein structure and function and for developing tools for protein structure modeling and design. We explored the frequency of occurrences of an exhaustively classified library of supersecondary structural ...

For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combination of) the following five criteria: (i) intergenic distance, (ii) conserved gene clusters, (iii) functional relation, (iv) sequence elements and (v) experimental evidence. The performance estimates of operon predic...

Identification of operon structure is critical to understanding gene regulation and function, and pathogenesis, and for identifying targets towards the development of new antibiotics in bacteria. Recently, the complete genome sequences of a large number of important human bacterial pathogens have become available for computational analysis, including the major human Gram-positive pathogen Staph...

This experimental study examines whether the content of information and the timing of its dissemination affects firms’ market power. We construct laboratory markets that capture the key features of a price-setting, differentiated goods, duopoly model analyzed by Anderson and Renault (2000). Consumers must typically incur a search cost in order to obtain any information, but a fraction of the co...

We study complex networks under random matrix theory (RMT) framework. Using nearest-neighbor and next-nearest-neighbor spacing distributions we analyze the eigenvalues of the adjacency matrix of various model networks, namely, random, scale-free, and small-world networks. These distributions follow the Gaussian orthogonal ensemble statistic of RMT. To probe long-range correlations in the eigenv...