نتایج جستجو برای: precancerous condition
تعداد نتایج: 320249 فیلتر نتایج به سال:
PURPOSE The objective of this study was to evaluate the diagnostic concordance characteristics of oral cavity lesions by comparing the clinical diagnosis of the lesions with the histopathologic diagnosis. MATERIAL AND METHOD A retrospective analysis was conducted on the patients, who were admitted with oral cavity pathology and underwent biopsy procedure between 2007 and 2011. The oral cavity...
Nicotine, a tumor promoter in tobacco, can increase Peroxiredoxin (Prx1) and nicotinic acetylcholine receptors (nAChRs) in oral squamous cell carcinoma (OSCC). In the present study, we investigate the effects of nicotine in oral precancerous lesions focusing on apoptosis and nAChR/Prx1 signaling. We detected expression of Prx1, α3nAChR, α7nAChR, phosphorylation of mitogen-activated protein kina...
Purpose: Qat chewing, smoking, smokeless tobacco (locally known as shammah) and waterpipe smoking (locally known as madaah) are common habits in Yemen. The aim of this study was to investigate the prevalence of oral cancerous and precancerous lesions, and to investigate the prevalence of oral risk habits among Yemeni adults attending outpatient dental clinics, Sana‘a University. Materials and m...
INTRODUCTION Chronic atrophic gastritis, intestinal metaplasia, hereditary non-polyposos colon cancer, gastric dysplasia, gastric adenoma, Barrett esophagitis and familiar adenomatous polyposis are confirmed precancerous lesions of the stomach. Most of these conditions are correlated with long-term infections with Helicobacter pylori. MATERIAL AND METHOD Patients which were included in our st...
Metal nanoparticles can function as optical contrast enhancers for reflectance-based diagnosis of epithelial precancer. We carry out Monte Carlo simulations to model photon propagation through normal tissues, unlabeled precancerous tissues, and precancerous tissues labeled with gold nanospheres and we compute the spectral reflectance response of these different tissue states. The results indica...
Although recent studies have suggested that tooth loss is positively related to the risk of gastric non-cardia cancer, the underlying oral health conditions potentially responsible for the association remain unknown. We investigated whether clinical and behavioral measures of oral health are associated with the risk of gastric precancerous lesions. We conducted a cross-sectional study of 131 pa...
Prostate cancer is the most frequently diagnosed form of cancer and the second leading cause of cancer related deaths in the United States. Increased consumption of soy is thought to reduce the risk for this disease. More specifically, the isoflavones found in soy are responsible, in part, for these anticancer effects. Isoflavones are organic compounds found in soy and other legumes and it is t...
Early detection and differential analysis of premalignant lesions are very important for both prognosis and therapy of cancer patients. A good source of diagnostic tools is the natural antibody pool of humans. Tumor-specific antibodies can be established by using hybridoma technology. The fully human germline-coded monoclonal IgM antibody PAM-1 was isolated from a patient with a stomach carcino...
Aims. Worldwide, cervical cancer is the fifth most deadly cancer in women, but screening prevents cancer by detecting precancerous lesions. The purpose of this study is to present the treatment profile for precancerous lesions of the uterine cervix, according to demographic data. Methods. An annual retrospective study was conducted in two public primary health care centres in Greece. The total ...
The development of the oral squamous cell carcinoma (OSCC) is a multistep process that requires the accumulation of multiple genetic alterations usually preceded by detectable mucosal changes, most often leukoplakias and erythroplakias. The clinical appearance of oral precancerous lesions and their degree of epithelium dysplasia suggests the malignization potential. Several techniques have been...
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