The human intestine hosts a complex bacterial community that plays a major role in nutrition and in maintaining human health. A functional metagenomic approach was used to explore the prebiotic breakdown potential of human gut bacteria, including non-cultivated ones. Two metagenomic libraries, constructed from ileum mucosa and fecal microbiota, were screened for hydrolytic activities on the pre...

As of today, the most credible scientific paradigm pertaining to the origin of life on Earth is undoubtedly the RNA World scenario. It is built on the assumption that catalytically active replicators (most probably RNA-like macromolecules) may have been responsible for booting up life almost four billion years ago. The many different incarnations of nucleotide sequence (string) replicator model...

Objective: In this study, 3% Lactobacillus rhamnosus and Bifidobacterium animalis subsp lactis BB-12 as probiotics 8% hazelnut paste banana pulp prebiotics were added to milk jam samples produce functional jam. Physical, chemical, sensorial microbiological properties of discussed during 30 days storage. Materials Methods: The stored at +4 °C for days. Physicochemical (proximate analysis, acidit...

One of the most important open issues in astrochemistry and astrobiology is the detection in space of complex organic molecules, in particular those having a strong prebiotic role (i.e., related to the formation of biomolecule building blocks), and the identification of the chemical routes for their production. By means of selected examples, the role of rotational spectroscopy and quantum chemi...

Packaged Facts estimates the global retail market for probiotic and prebiotic foods and beverages at approximately $15.4 billion in 2008; that total represents a 12.5% increase over estimated 2007 sales of $13.7 billion. In 2008, the growth rate for the probiotic and prebiotic food and beverage market ranged from 5% to more than 30%, depending on the region and product type. Packaged Facts anal...

The search for prebiotic, nucleic acid precursors is, at its best, a speculative undertaking. Given the complex structure of RNA, it is not very likely that RNA was the first information system in the universe and thus finding possible precursor/s i.e. pre-RNA remains an open challenge. We, in this paper, have tried to construct nucleic acid polymers with a simple acyclic, achiral backbone. Suc...