OBJECTIVE: To analyse whether prealbumin could be a new biomarker for predicting mortality in severe COVID-19 patients. STUDY DESIGN: An observation study. PLACE AND DURATION OF STUDY: Intensive care units (ICU) of Sakarya University Training and Research Hospital, Sakarya, Turkey, from October 2020 to December 2020. METHODOLOGY: The data 149 patients, who were admitted the ICU collected analys...

of a yellow Fe3tcitrate complex [calibration curve (A = 390 nm) was linear from 52.9 to 696.6 pmol/L, n = 8, r = 1.000; SD = 0.9; F = 263224.4; average relative error 0.3%]. Phosphate, which can interfere, is eliminated by precipitation. The usual procedui-e is as follows: To 4 mL of sample, add 0.1 mL of NH4OH (30%) and 0.9 mL of Mg2 (0.2 mol/L) and filter. Then adjust the pH to 2(0.1 mL of 10...

A radioimmunoassay (RIA) for human thyroxine-binding prealbumin (PA) is described. It employs highly purified PA, anti-human PA serum at 1:30,000 final dilution, normal bovine serum as a carrier, and polyethyleneglycol to precipitate the immune complexes. This assay is extremely sensitive (limit of detection less than 0.2 micrograms per dL or less than 3.6 X 10(-15) moles per tube), accurate (r...

Background Elevated cerebrospinal fluid (CSF) total protein (TP) concentration (mainly due to a dysfunctional blood-CSF barrier (B-CSFB)) with normal cell count is a hallmark for the diagnosis of Guillain-Barré syndrome (GBS). Aims This work presents the evaluation of B-CSFB dysfunction with respect to the course, severity, and clinical features of GBS. Materials and Methods A sample of CSF was...

Few studies have tried to characterize the efficacy of parenteral support of critically ill infants during short period of intensive care. We studied seventeen infants during five days of total parenteral hyperalimentation. Subsequently, according to the clinical conditions, the patients received nutritional support by parenteral, enteral route or both up to the 10th day. Evaluations were perfo...

Idiopathic nephrotic syndrome (NS) is the most common glomerular disorder of childhood. Response to initial treatment with corticosteroids is an indicator of prognosis, as resistant patients often present more progressive disease. In this cross-sectional pilot study, we set out to discover a panel of noninvasive biomarkers that could distinguish steroid-resistant nephrotic syndrome (SRNS) from ...

Aim: Nutritional indicators are associated with adverse outcomes in critically ill elderly patients. In this study, we aimed to evaluate the prognostic potential of prealbumin and albumin prediction mortality patients sepsis. Material Method: A total 108 who developed intensive care unit-acquired sepsis were divided into two groups: Survivors (n=72) Non-survivors (n=36). Results: Patients group...

10. Amino N, Nishi K, Nakatani K, et al. Effect of albumin concentration on the assay of serum free thyroxin by equilibrium radioimmunoassay with labeled thyroxin analog (Amerlex#{174} F’reeT4). Clin C/tern 29, 321-325 (1983). 11. Stockigt JR, Stevens V, White EL, Barlow JW. “Unbound analog” radioimmunoassay methods for free thyroxin measure the albumin-bound hormone fraction. Clin C/tern 29, 1...