نتایج جستجو برای: pr 1

تعداد نتایج: 2771269  

Journal: :Molecular endocrinology 1999
M J Tetel P H Giangrande S A Leonhardt D P McDonnell D P Edwards

Full transcriptional activation by steroid hormone receptors requires functional synergy between two transcriptional activation domains (AF) located in the amino (AF-1) and carboxyl (AF-2) terminal regions. One possible mechanism for achieving this functional synergy is a physical intramolecular association between amino (N-) and carboxyl (C-) domains of the receptor. Human progesterone recepto...

Journal: :Endocrinology 2008
Heather A Molenda-Figueira Suzanne D Murphy Katherine L Shea Nora K Siegal Yingxin Zhao Joseph G Chadwick Larry A Denner Marc J Tetel

In vitro studies reveal that nuclear receptor coactivators enhance the transcriptional activity of steroid receptors, including estrogen (ER) and progestin receptors (PR), through ligand-dependent interactions. Whereas work from our laboratory and others shows that steroid receptor coactivator-1 (SRC-1) is essential for efficient ER and PR action in brain, very little is known about receptor-co...

2010
Oliver Löwenstein Petra Leyendecker Eberhard A Lux Mark Blagden Karen H Simpson Michael Hopp Björn Bosse Karen Reimer

BACKGROUND Two randomised 12-week, double-blind, parallel-group, multicenter studies comparing oxycodone PR/naloxone PR and oxycodone PR alone on symptoms of opioid-induced bowel dysfunction in patients with moderate/severe non-malignant pain have been conducted. METHODS These studies were prospectively designed to be pooled and the primary outcome measure of the pooled data analysis was to d...

Journal: :The Journal of biological chemistry 1991
N V Rao N G Wehner B C Marshall W R Gray B H Gray J R Hoidal

Proteinase 3 (PR-3) is a human polymorphonuclear leukocyte (PMNL) serine proteinase that degrades elastin in vitro and causes emphysema when administered by tracheal insufflation to hamsters (Kao, R. C., Wehner, N. G., Skubitz, K. M., Gray, B. H., and Hoidal, J. R. (1988) J. Clin. Invest. 82, 1963-1973). We have determined the primary structure of several PR-3 peptides and have analyzed catalyt...

Journal: :Journal of Combinatorial Theory, Series A 1982

2005
Taiichiro SEKI Ryohei NAGASE Mariko TORIMITSU

served in Japan. PR has been developed industrially in order to enhance the nutritional functions of its source material, brown rice (BR). PR is produced by soaking BR in water for slight germination. Amounts of some constituents including g-aminobutyric acid (GABA) are remarkably increased in PR. GABA is also known to potentiate the insulin secretion in pancreas. Thus PR is thought to ameliora...

ژورنال: :مجله پزشکی ارومیه 0
علیرضا رستم زاده alireza rostamzadeh assistant professor, cardiology department, seyed-al-shohada cardiac specialized hospital, urmia university of medical sciences, urmia, iranاستادیار گروه قلب، دانشگاه علوم پزشکی ارومیه، ارومیه، ایرانسازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (urmia university of medical sciences) کمال خادم وطن kamal khademvatani cardiology department, seyed-al-shohada cardiac specialized hospital, urmia university of medical sciences, urmia, iran: ارومیه، دانشگاه علوم پزشکی ارومیه، گروه قلب، تلفن: 09141418525سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (urmia university of medical sciences)

پیش زمینه و هدف: در این مطالعه هدف ما بررسی درجه اهمیت بالینی نزول pr بعد از mi در پیش آگهی افراد مبتلا به سکته قلبی حاد می باشد. مواد و روش کار: در این مطالعه توصیفی تحلیلی، اولین نوار قلب تمام بیمارانی که به دلیل سکته قلبی در بیمارستان طالقانی بستری شده بودند، ازنظر افت قطعه pr موردبررسی قرار گرفتند. بر این اساس، بیماران به دو گروه ازنظر افت قطعه pr تقسیم شدند و هر دو گروه را ازنظر عوارض قلبی...

2015
Kalpana D. Acharya Sarah D. Finkelstein Elizabeth P. Bless Sabin A. Nettles Biserka Mulac-Jericevic Orla M. Conneely Shaila K. Mani Marc J. Tetel

Estrogens act in brain to profoundly influence neurogenesis, sexual differentiation, neuroprotection, cognition, energy homeostasis, and female reproductive behavior and physiology through a variety of mechanisms, including the induction of progestin receptors (PRs). PRs are expressed as two isoforms, PR-A and PR-B, that have distinct functions in physiology and behavior. Because these PR isofo...

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