BACKGROUND Picropodophyllin (PPP) is a promising novel anti-neoplastic agent that efficiently kills tumor cells in vitro and causes tumor regression and increased survival in vivo. We have previously reported that PPP treatment induced moderate tolerance in two out of 10 cell lines only, and here report the acquired genomic and expression alterations associated with PPP selection over 1.5 years...

Precise Point Positioning (PPP) has become a very hot topic in GNSS research and applications. However, it usually takes about several tens of minutes in order to obtain positions with better than 10 cm accuracy. This prevents PPP from being widely used in real-time kinematic positioning services, therefore, a large effort has been made to tackle the convergence problem. One of the recent appro...

Several Extensible Authentication Protocol (EAP) [EAP] authentication methods employ X.509 public key certificates. For example, EAP-TLS [EAP-TLS] can be used with PPP [PPP] as well as IEEE 802.1X [802.1X]. PPP is used for dial-up and VPN environments. IEEE 802.1X defines port-based, network access control, and it is used to provide authenticated network access for Ethernet, Token Ring, and Wir...

Several Extensible Authentication Protocol (EAP) [EAP] authentication methods employ X.509 public key certificates. For example, EAP-TLS [EAP-TLS] can be used with PPP [PPP] as well as IEEE 802.1X [802.1X]. PPP is used for dial-up and VPN environments. IEEE 802.1X defines port-based, network access control, and it is used to provide authenticated network access for Ethernet, Token Ring, and Wir...

This paper is a submission to the OOPSLA 2000 workshop "Mining Pedagogical Patterns". It briefly describes some of the problems of the current state of the PPP and tries to give some proposals as to how to improve the situation. In particular, it describes an alternative form for pedagogical patterns, it tries to formalize a schema for categorization of the patterns and the relationships among ...

(+)3H-3-PPP [(+)3H-3-(3-Hydroxyphenyl)-N-(1-propyl)-piperidine] binds with high affinity to brain membranes with a pharmacological profile consistent with that of sigma receptors. The distribution of (+)3H-3-PPP binding sites in brain and spinal cord of both guinea pig and rat has been determined by in vitro autoradiography with binding densities quantitated by computer-assisted densitometry. (...

Background:The utility and efficacy of novel materials in tissue regeneration and antimicrobial therapy are contingent upon the employment of either blood derivatives rich in platelets or platelet-poor-plasma (PPP). This effect is largely mediated by the increased or decreased concentration of platelets in the plasma. The current study aimed t...

Status of this Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Abstract The Point-to-Point Protocol (PPP) [1] provides a standard method for transporting multi-protocol datagrams over point-to-point links. This document describes how to build PPP sessions and encapsulate PPP packets ove...

Studies concerning the anatomical abnormalities of upper airways in patients affected by Obstructive Sleep Apnea Syndrome (OSAS) allowed the corrective surgical treatments in this syndrome. To provide an improvement or a definitive recovery of OSAS, various surgical treatments, i.e. functional nasal surgery, palatal surgery [Partial resection of palate (RPP), Uvulopalatopharingoplasty (UPPP), P...