Detailed analysis of data from studies of recombinant antihemophilic factor produced using a plasma/albumin-free method (rAHF-PFM) in previously treated patients showed a substantial level of interpatient variation in pharmacokinetics (PKs), factor VIII dosing, and annualized bleed rate (ABR), suggesting that individual patient characteristics contributed to outcome. For example, plasma half-li...

Abstract Phase-field method (PFM) has become a mainstream computational for predicting the evolution of nano and mesoscopic microstructures properties during materials processes. The paper briefly reviews latest progresses in applying PFM to understanding thermodynamic driving forces mechanisms underlying microstructure metallic related processes, including casting, aging, deformation, additive...

Hysteresis loop analysis via piezoresponse force microscopy (PFM) is typically performed to probe the existence of ferroelectricity at the nanoscale. However, such an approach is rather complex in accurately determining the pure contribution of ferroelectricity to the PFM. Here, we suggest a facile method to discriminate the ferroelectric effect from the electromechanical (EM) response through ...

Piezoresponse force microscopy (PFM) is one of the most established techniques for the observation and local modification of ferroelectric domain structures on the submicron level. Both electrostatic and electromechanical interactions contribute at the tip-surface junction in a complex manner, which has resulted in multiple controversies in the interpretation of PFM. Here we analyze the influen...

The phase-field microelasticity (PFM) is adapted into a homogenization process to predict all the effective elastic constants of three-dimensional heterogeneous materials with complex microstructures. Comparison between the PFM approach and the Hashin–Shtrikman variational approach is also given. Using 3D images of two-phase heterogeneous media with regular and irregular microstructures, result...

MOTIVATION Transcription factors (TFs) play a key role in gene regulation by binding to target sequences. In silico prediction of potential binding of a TF to a binding site is a well-studied problem in computational biology. The binding sites for one TF are represented by a position frequency matrix (PFM). The discovery of new PFMs requires the comparison to known PFMs to avoid redundancies. I...

Feature transformation aims to reduce the effects of channeland handset-distortion in telephone-based speaker verification. This paper compares several feature transformation techniques and evaluates their verification performance and computation time under the 2000 NIST speaker recognition evaluation protocol. Techniques compared include feature mapping (FM), stochastic feature transformation ...

OBJECTIVES Evaluation of resting and functional bioelectrical activity of the pelvic floor muscles (PFM) and the synergistic muscles, depending on the orientation of the pelvis, in anterior (P1) and posterior (P2) pelvic tilt. DESIGN Preliminary, prospective observational study. SETTING Department and Clinic of Urology, University Hospital in Wroclaw, Poland. PARTICIPANTS Thirty-two menop...

The aim of the study was an assessment of isometric torque (IT) values under static conditions and relative torque (RT) for the plantar flexion muscles (PFM) and dorsal flexion muscles (DFM) and their mutual relations in males 5 years after talocrural joint sprain. IT measurements in PFM and DFM were performed using Biodex System 3. Group I consisted of 20 males on average 5 years after the spr...