Metal-organic frameworks are compounds with a reticulated skeletal structure formed by chemically bonding inorganic and organic units that widely used in many fields, such as photocatalysis, gas separation energy storage, because of their unique structures. In this paper, we prepared metal-organic framework [(μ2-2-methylimidazolyl)12-Zn(ii)6-H18O10]n(ZM) well-developed pores high specific surfa...

We describe a 21 month old male infant who presented with failure to thrive associated with severe hypokalaemia and metabolic acidosis, together with hypomagnesaemia. Evaluation revealed marked renal and probable faecal potassium wasting, distal renal tubular acidosis, mild urinary magnesium wasting, and a normal gastric pH (gastric H(+)-K(+)-ATPase). Hypokalaemic forms of metabolic acidosis, s...

Compared with the Stone Age diet, the modern human diet is both excessive in NaCl and deficient in fruits and vegetables which are rich in K+ and HCO3- -yielding organates like citrate. With the modern diet, the K+/Na+ ratio and the HCO3-/Cl- ratio have both become reversed. Yet, the biologic machinery that evolved to process these dietary electrolytes remains largely unchanged, genetically fix...

Neurons from bullfrog sympathetic ganglia were voltage-clamped using a single microelectrode in Ringer solution with tetrodotoxin. The M-current (Adams et al. 1982 a) was markedly reduced during the rhythmic outward potassium current induced by caffeine (1-5 mM). This indicates that an elevation of the intracellular concentration of calcium ions by caffeine not only activates the calcium-activa...

The native form of ATP citrate lyase (2 mol of phosphate/tetramer) and the dephospho-ATP citrate lyase (phosphate-free) purified to homogeneity from rat liver, are phosphorylated by ATP and by the catalytic subunit of cAMP-dependent protein kinase from rabbit muscle. A total of 2 mol of phosphate/tetramer were incorporated into native enzyme, while with the dephospho form, 4 mol of phosphate we...

BACKGROUND The use of a combination of different drugs in postoperative analgesia extends the time of analgesia, makes it more efficient and allows the use of lower drug doses, which leads to less risk of side effects and drug dependence. The aim of this study was to develop and validate an HPLC method to determine the stability of fentanyl citrate and bupivacaine hydrochloride mixtures in stan...