BACKGROUND Glaucoma is the leading cause of irreversible blindness worldwide. There tends to be a lower reporting of glaucoma in Africa compared to other blinding conditions in global burden data. Research findings of glaucoma in Nigeria will significantly increase our understanding of glaucoma in Nigeria, in people of the West African diaspora and similar population groups. We determined the p...

Purpose To compare the levels of autotaxin (ATX), lysophosphatidic acid (LPA), and lysophosphatidylcholine (LPC) in the aqueous humor (AH) of healthy control subjects with those of patients with different subtypes of glaucoma, and also to investigate the relationship of the ATX-LPA pathway with IOP and subtype of glaucoma. Methods This study included 164 eyes of 164 consecutive cases of catar...

BACKGROUND To determine the outcome of central retinal vein occlusion (CRVO) in pre-existing glaucoma and the predisposing factors of developing neovascular glaucoma (NVG). METHODS We retrospectively assessed a pre-existing glaucoma CRVO group and a non-glaucoma CRVO group to elucidate the demographics, clinical course and ocular parameters of these two cohorts. Among the pre-existing glaucom...

purpose : to investigate the impact of socioeconomic factors on presenting severity of glaucoma methods : in a cross-sectional study at farabi eye hospital, and during 12 months study period, 258 patients with newly diagnosed glaucoma were enrolled and socioeconomic status of the patients were evaluated. results : lower socioeconomic score was associated with higher intraocular pressure (r=-0.3...

PURPOSE To investigate the outcomes of childhood glaucoma suspects. DESIGN Retrospective case series. METHODS Records of childhood glaucoma suspects were identified using financial claims data; medical history, baseline biometric and exam findings were recorded. Conversion from suspect to glaucoma was determined based on the Childhood Glaucoma Research Network criteria. The study adheres to...

Glaucoma is a multifactorial optic neuropathy characterized by retinal ganglionic cell death. Elevated intraocular pressure (IOP) is a recognized risk factor for retinal ganglionic cell degeneration in glaucoma, but is it the only cause of glaucoma? Do progression of glaucoma is fully controlled by controlling IOP? No. Today there are enormous pharmacological and surgical methods to control IOP...

INTRODUCTION Malignant glaucoma occurs when the intraocular pressure elevates in the setting of a shallow anterior chamber and patent iridectomy. We describe a case in which malignant glaucoma that was refractory to conventional treatment and complete vitrectomy was successfully managed by rerouting the glaucoma tubes into the pars plana. CASE PRESENTATION A 47-year-old Latino man had a histo...

Glaucoma is a major blinding condition and is more prevalent amongst the elderly. A population study of 479 elderly Chinese aged 60 years and older, and residing in Singapore was carried out to determine the prevalence of glaucoma. The overall glaucoma prevalence was 4.8% with normal tension glaucoma (61%) and primary angle closure glaucoma (26%) being the most prevalent forms of glaucoma. All ...

Background: Axenfeld-Rieger syndrome (ARS), a developmental disorder, involves anterior segment abnormalities and can lead to glaucoma. However, limited research has addressed the ultrasound biomicroscopy (UBM) characteristics of ARS. This study aimed assess chamber angle features using UBM in ARS determine their correlation with glaucoma severity mutant genes.

Background: Glaucoma refers to a heterogeneous group of diseases characterized by retinal cell degeneration and optic nerve atrophy leading blindness. Even though about 40% patients have normal intraocular pressure (IOP), current treatment. focuses on lowering IOP. With time, drugs become less effective, which has motivated the search for novel drugs.The objective was establish whether modulato...