Keratoconus is an ectatic corneal dystrophy associated with stromal thinning and disruption of Bowman's layer. The purpose of this study was to explore a possible association between keratocyte apoptosis and keratoconus. Keratocyte apoptosis was evaluated in corneas of patients with keratoconus, corneas of patients with stromal dystrophies, and normal donor corneas using the transferase-mediate...

Acute keratoconus is the term applied to the sudden development of a gross degree of corneal oedema in a patient with a pre-existing keratoconus. This rare condition was probably first described by Terrien (I906). An association between mongolism and acute keratoconus has recently been observed, the first two cases having been reported by Hoffmann (I956). Three cases (two bilateral) are reporte...

PURPOSE To determine the repeatability of corneal thickness measurements with Scheimpflug (Pentacam) and slit scanning (Orbscan) imaging techniques in different grades of keratoconus. METHODS This study was conducted as a cross-sectional research. Imaging with Orbscan and Pentacam was performed on patients with different grades of keratoconus. With each device, 3 measurements were taken at 10...

BACKGROUND Keratoconus normally presents as a sporadic disease. Although different studies have found sequence variants of the visual system homeobox 1 (VSX1) gene associated with keratoconus in humans, no research has detected such variants in sporadic keratoconus patients from China. To investigate the possibility of VSX1 being a candidate susceptibility gene for Chinese patients with sporadi...

purpose: to evaluate the safety, efficacy, stability and predictability of posterior chamber collagen copolymer phakic intraocular lens (piol) implantation to correct myopia and myopic astigmatism in keratoconus-affected patients. methods: uncorrected (ucva) and best-corrected (bcva) distance visual acuity, refraction and complications were evaluated in 22 keratoconic eyes of 14 patients who un...

Background: This study aimed to investigate the diagnostic value of pachymetry parameters measured by RTVueOCT for keratoconus. Methods: 74 patients with 118 eyes diagnosed with keratoconus were enrolled in keratoconus group and 60 patients with normal 120 eyes as health controls. Pachymetry parameters were measured. The major indicators were tested: 1) S-I value: difference between the mean su...

Purpose. The purpose of this study is to evaluate the vision related quality of life in patients with keratoconus by using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25). Methods. Thirty patients presented with keratoconus (keratoconus group) and 30 healthy patients (control group) were included in this study. Twenty patients were using rigid gas permeable and 10 patie...

We report a case of a 21-year-old male patient who underwent corneal cross-linking (CXL) due to bilateral progressive keratoconus. Topographical screening of his family members was performed for the detection of possible familial keratoconus and showed abnormal topographical patterns resembling to Forme Fruste Keratoconus (FFK) in all the members of his family. The reported keratoconic patient ...

Keratoconus has usually been described as bilateral but asymmetric disease. Corneal ectasia is one of the long-term complications of modern refractive surgery, especially those submitted to laser in situ keratomileusis (LASIK). We describe a patient with keratoconus in the right eye that was submitted to radial keratectomy (RK) in the left eye 19 years ago with no progression of the ectatic cor...