BACKGROUND AND PURPOSE Stroke is the major cause of vascular behavior and cognitive disorders worldwide. In developing countries, there is a dearth of information regarding the public health magnitude of stroke. The aim of the Fogarty-Mexico cohort was to assess the prevalence of vascular behavioral and cognitive disorders, ranging from mild vascular cognitive impairment (VCI) to vascular demen...

impairment no-dementia influence the outcome of patients treated by intravenous thrombolysis for cerebral ischaemia? Approximately 10% of patients with a first-ever stroke and 30% with a recurrent stroke have pre-existing dementia, 1 and many others have cognitive impairment no-dementia (CIND). A recent trial and an updated meta-analysis showed that

OBJECTIVES Although stroke associated with small vessel disease (SSVD) can induce both motor and cognitive impairment, the latter has received less attention. We aimed to evaluate the frequency of the varying severity levels of cognitive impairment, the determinants of severe cognitive impairment, and the association of cognitive impairment with functional outcome after SSVD. METHODS Consecut...

We determined the frequency of dementia in a cohort of 251 patients aged greater than or equal to 60 years hospitalized with acute ischemic stroke, based on examinations performed 3 months after stroke onset. Using modified DSM-III-R criteria, we found dementia in 66 patients (26.3%). Diagnostic agreement among raters was excellent (kappa = 0.96). In a control sample of 249 stroke-free subjects...

BACKGROUND AND PURPOSE Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at 3 and 15 months with a detailed neuropsychological evaluation (including me...

Aging nations are growing worldwide and now one in four of us may expect to experience an ischemic brain injury by the age 85. Stroke is the third most common cause of death and the second most common cause of dementia in industrialized societies with a mortality rate of circa 30% and an incidence of about 250–400 in 100,000. Stroke affects circa 700,000 people each year in the US alone, and ab...

Citicoline or CDP-choline (cytidine-5'-diphosphate choline), is one of the most frequently prescribed drugs for cognitive impairment in several countries worldwide [1-3]. It is composed of ribose, pyrophosphate, cytosine (a nitrogenous base) and choline. In clinical practice, a number of different studies have shown that citicoline is effective in cognitive impairment (CI) of diverse etiology, ...

OBJECTIVES To explore the association between prestroke mobility dependency and dementia on functioning and mortality outcomes after stroke in patients>65 years of age. DESIGN Longitudinal cohort study based on SveDem, the Swedish Dementia Registry and Riksstroke, the Swedish Stroke Registry. PARTICIPANTS A total of 1689 patients with dementia >65 years of age registered in SveDem and suffe...

BACKGROUND Vascular dementia is extremely common and contributes to stroke-associated morbidity and mortality. The study of vascular dementia may help to plan preventive interventions. AIMS To study the frequency of cognitive impairment after stroke in a series of consecutive patients with acute stroke, along with factors which influence it. METHODS Fifty adults with acute infarct or hemorr...