Objective: The study aimed to identify the factors affecting the prognosis of post myocardial infarction (MI) ventricular septal rupture (VSR) and to develop a protocol for its management. Methods: This was a single center, retrospective-prospective study (2009-2014), involving 55 patients with post MI VSR. The strengths of association between risk factors and prognosis were assessed using mu...

BACKGROUND We sought to investigate the relationship between infarct and dyssynchrony post- myocardial infarct (MI), in a porcine model. Mechanical dyssynchrony post-MI is associated with left ventricular (LV) remodeling and increased mortality. METHODS Cine, gadolinium-contrast, and tagged cardiovascular magnetic resonance (CMR) were performed pre-MI, 9 ± 2 days (early post-MI), and 33 ± 10 ...

Rationale: We recently demonstrated that proteolytic cleavage fragments of cardiac myo-sin binding protein-C (cMyBP-C) can be detected in the serum after myocardial infarction (MI) in a rat model and in patients with MI. The findings implied that serum cMyBP-C might be useful as cardiac-specific biomarker for MI. The release kinetics of cMyBP-C in the circulation post-MI remains to be elucidate...

In the post-myocardial infarction (MI) patient with coronary artery disease (CAD) and left ventricular dysfunction (LVD), ischemia and adverse remodeling hinder myocardial performance and increase electrical instability. Collectively, the coronary arteries, myocardium, and conduction system represent the principal pathophysiologic targets in MI complicated by LVD and subsequent failure. Patient...

Objective Patients with rheumatoid arthritis (RA), have an increased risk of fatal myocardial infarction (MI) that might be explained by an increased inflammatory burden of the heart. We investigated inflammatory cell density in heart tissue of deceased patients with RA and MI and compared them with controls with MI but without RA. Methods Tissue-slides of the infarct related coronary artery an...

OBJECTIVE A meta-analysis of over 25 years of research into the relationship between post-myocardial infarction (MI) depression and cardiac prognosis was conducted to investigate changes in this association over time and to investigate subgroup effects. METHOD A systematic literature search was performed (Medline, Embase and PsycINFO; 1975–2011) without language restrictions. Studies investig...

Beta-blockers are effective agents for secondary prevention post-myocardial infarction (MI). They have antiarrhythmic, anti-ischemic, and antihypertensive effects that decrease morbidity and mortality in patients after an MI. Critical care nurses can play an active role in recognizing those patients, especially high-risk individuals, who may benefit from beta-blocker therapy.

UNLABELLED In 2005, Chile implemented a universal system of health guarantees (AUGE) aimed at improving equitable access to quality medical care for priority health conditions, including acute myocardial infarction (MI). OBJECTIVE To evaluate 1-year survival in MI patients before and after AUGE. METHODS Retrospective cohorts of patients with MI (with and without ST segment elevation) discha...

OBJECTIVES We sought to determine the predictors of heart failure (HF) development in long-term survivors of myocardial infarction (MI). BACKGROUND Modern strategies of acute MI care have resulted in an increasing proportion of survivors at heightened risk of future non-fatal events, including HF. METHODS We assessed the risk of developing HF in 3860 stable MI patients without a previous hi...

Background—Atrial fibrillation (AF) often coexists with myocardial infarction (MI), yet its prognostic influence is disputed. Prior reports studied the relationship of AF during early hospitalization for acute MI to the risk of death and could not address the timing of AF in relation to the MI (ie, before, during, after). Furthermore, as data come mostly from clinical trials, their applicabilit...