The analysis of population-wide datasets can provide insight on the health status large populations so that public officials make data-driven decisions. such often requires highly parameterized models with different types fixed and random effects to account for risk factors, spatial temporal variations, multilevel other sources uncertainty. To illustrate potential Bayesian hierarchical models, ...

The characterization of molecular changes in diseased tissues can provide crucial information about pathophysiological mechanisms and is important for the development of targeted drugs and therapies. However, many disease processes are accompanied by changes of cell populations due to cell migration, proliferation or death. Identification of key molecular events can thus be overshadowed by conf...