نتایج جستجو برای: poorly water soluble drugs
تعداد نتایج: 924239 فیلتر نتایج به سال:
Microemulsions are an intriguing method for delivering poorly soluble drugs, protecting labile controlling drug release, and increasing bioavailability. They can be given topically, orally, or intravenously, use polyethylene glycol (PEG-400) as a co-surfactant to improve the solubility stability of biological classification system (BCS) class II drugs. The goal this research is develop test oil...
Quantitative spectrophotometric analysis of poorly water-soluble drugs involves use of various organic solvents. Major drawbacks of organic solvents include high cost, volatility and toxicity. Safety of analyzer is affected by toxicity of the solvent used. In the present investigation the use of organic solvent has been avoided, making the method environmentally friendly. Urea has demonstrated ...
BACKGROUND A microemulsion is an effective formulation for improving the oral bioavailability of poorly soluble drugs. In this paper, a water-in-oil (w/o) microemulsion was investigated as a system for enhancing the oral bioavailability of Biopharmaceutic Classification System (BCS) III drugs. METHODS The microemulsion formulation was optimized using a pseudoternary phase diagram, comprising ...
Self nano emulsifying drug delivery systems (SNEDDs) gained much attention in the last decades since, such considered one of most favorable and efficient approaches to enhance solubility, increase absorption hence, its oral bioavailability poorly water soluble (lipophilic) moieties. Owing their unique properties advantages over other conventional dosage forms, many literatures investigate chang...
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