Cefpodoxime Proxetil (Poorly water soluble drug), when prepared as solid dispersion showed improved solubility and dissolution. So the main purpose of this investigation was to increase the solubility and dissolution rate of Cefpodoxime Proxetil by the preparation of its solid dispersion with urea using solvent evaporation method. Physical mixtures and solid dispersions of Cefpodoxime Proxetil ...

Self nano emulsifying drug delivery systems (SNEDDs) gained much attention in the last decades since, such considered one of most favorable and efficient approaches to enhance solubility, increase absorption hence, its oral bioavailability poorly water soluble (lipophilic) moieties. Owing their unique properties advantages over other conventional dosage forms, many literatures investigate chang...