BACKGROUND Treatment with steroids covers a wide spectrum of diseases in clinic. However, some users are suffering from serious side effects of steroid administration, while we enjoy the benefit it brings about. Osteonecrosis of the femoral head (ONFH) is a troublesome one among them. Recent studies have demonstrated that lipid metabolism disorder may play a vital role in pathogenesis of ONFH a...

The National Sports Week (known in Bahasa Indonesia as Pekan Olahraga Nasional or PON) consumes a large budget Indonesia’s largest multi-sports event. This raises the question of whether it is only sporting event has an impact on society. Studies related to events, specifically form local small-scale, such PON, are still limited Asia. aim this study was investigate six important domains (constr...

This paper studies the business case of migration from legacy FTTH networks like active star Ethernet and GPON towards NG-AON and TWDM-PON for a network provider, evaluating its techno-economic viability and suggesting possible improvements. Introduction and motivation It is clear that all-fiber networks are the future for telecommunications access. Although the current technologies, such as ac...

Indonesia National Sports Games (PON XX) has been successfully held far away from the capital city Jakarta. Located in Papua, PON 20th became first national sports event hosted east of Indonesia’s province. The agenda is more than just a quadrennial sporting for Indonesian Government. become an instrument strategy soft diplomacy that aimed to deal with domestic and international issues Papua. T...

PON(Passive Optical Network) is the most promising technology applicable to TPS(Triple Play Service). To improve network efficiency, MAC(Multiple Access Control) is the most important technology in the PON. This study develop BR(Borrow-Refund)-DBA for improve network efficiency and prompt process. For performance evaluation, simulated about throughput, fairness and queue delay in SR-DBA and NSR...

Today’s access networks are in high demand to fulfill the bandwidth requirement because of extensive improvement transmission rate applications for cloud computing, big data analytics, and other next-generation 5G smart applications. This exponential growth capacity broadband technologies comprise an essential trend development a passive optical network (PON) network. In this paper, 80/80 Gbps ...

BACKGROUND Immune thrombocytopenia (ITP) is the most common cause of acquired childhood thrombocytopenia and is characterized by increased immune-mediated destruction of circulating thrombocytes. Oxidative damage may be involved in ITP pathogenesis; paraoxonase (PON) and arylesterase (ARE) enzymes are closely associated with the cellular antioxidant system. We investigated the effect of short-t...

Previous studies have shown association of single nucleotide polymorphisms (SNPs) in 3 contiguous genes (PON1, PON2, and PON3) encoding paraoxonase with risk of Alzheimer disease (AD). We evaluated the association of serum paraoxonase activity measured by phenyl acetate (PA) and thiobutyl butyrolactone (TBBL) with risk of AD and with 26 SNPs spanning the PON gene cluster in 266 AD cases and 306...

Unequal segregation of cell fate determinants at mitosis is a conserved mechanism whereby cell fate diversity can be generated during development. In Drosophila, each sensory organ precursor cell (SOP) divides asymmetrically to produce an anterior pIIb and a posterior pIIa cell. The Par6-aPKC complex localizes at the posterior pole of dividing SOPs and directs the actin-dependent localization o...

BACKGROUND Carbon monoxide poisoning (COP) is an important cause of mortality and morbidity worldwide. This study was to investigate the levels of serum paraoxonase (PON), arylesterase (ARYL), ceruloplasmin (Cp), and sulfhydryl (-SH) in the treatment of COP, and to further understand the pathophysiology of COP. METHODS This prospective study comprised 107 individuals with COP (group 1) and 50...