in recent years, utilization of chitosan /tripolyphosphate nanoparticles has been considered greatly as protein delivery vehicles. effects of a variety of factors on final characteristics of nanoparticles have been studied by many investigators. although, the objective of this study was to achieve smaller chitosan nano carriers via changing fabrication parameters such as ph and temperature and ...

BACKGROUND Polymeric micelles using amphiphilic macromolecules are promising vehicles for antitumor targeting. In this study, we prepared anticancer agent-incorporated polymeric micelles using novel block copolymer. METHODS We synthesized a block copolymer composed of dextran and poly (DL-lactide-co-glycolide) (DexbLG) for antitumor drug delivery. Doxorubicin was selected as the anticancer dr...

We show that three different morphologies exist near the two-phase boundary of ternary systems containing a hydrotropic cosolvent. Based on synchrotron small- and wide-angle X-ray scattering combined with molecular dynamics, we rationalize the specific scattering signature of direct, bicontinuous, and reverse mesoscale solubilization. Surprisingly, these mesostructures are resilient toward stro...

The inactivation of spores of Penicillium oxalicum by supercritical carbon dioxide (SC-CO2) was optimized by response surface methodology. The optimal inactivation conditions of 16.8 MPa, 49°C, and 20 min were determined using ridge analysis, at which the predicted and experimental log10 reductions were obtained as 5.74 and 6.12, respectively. The synergistic effect of a cosolvent (ethanol), wh...

Mesoporous silica SBA-15 in the form of 10-30 μm sized sheets with unusually large ordered pores has been synthesized using heptane as a cosolvent in the presence of NH4F. The resulting morphology of 400 nm thick sheets that contain easily accessed, hexagonally arranged, 18 nm sized pores running parallel to sheet normal has not been previously reported. The material has a BET surface area of 5...

Microorganisms play critical roles in the various aquatic systems forming microbial mats. The microbial mats are held together and bound to their substrates by slimy extracellular polymeric substances (EPS) having various applications which they secrete. They use all types of metabolism and feeding strategy that have evolved on Earth, and have shown immense use in various industrial application...

reducing co2 emission and lowering the concentration of greenhouse gases in the atmosphere has quickly become one of the most urgent environmental issues. while a variety of technologies and methods have been developed, the separation of co2 from gas streams is still a critical issue. apart from establishing new techniques, the exploration of membrane materials with high separation performance ...

Under a wide variety of conditions, the addition of condensing agents to dilute solutions of random-coil DNA gives rise to highly compact particles that are toroidal in shape. The size of these condensates is remarkably constant and is largely independent of DNA molecular weight and basepair sequence, and of the nature of condensing agent (e.g., multivalent cation, polymers, or added cosolvent)...