The lumen of the nuclear pore complex is increasingly understood to be lined by a polymer brush that entropically regulates transport in and out of the nucleus—and it seems likely that similar effects probably arise with glycocalyx-lined holes in cell membranes. Here we mimic such poreconfined brushes with self-assembled polymer membranes imbued with nano-holes. Experiment and theory help eluci...

Nanoporous templates have been developed and fabricated employing technology based on heavy ion bombardment and track etching of polymer films or polymer layers deposited on substrates; an alternative and unique tool based on the adaptation of an atomic force microscopy has been also developed to elaborate nanotemplates with pores of ultra-small dimensions down to a few nanometers. Different ty...

Graphene oxide (GO) has been extensively explored in nanomedicine for its excellent physiochemical, electrical, and optical properties. Here, polyethylene glycol (PEG) and polyethylenimine (PEI) are covalently conjugated to GO via amide bonds, obtaining a physiologically stable dual-polymer-functionalized nano-GO conjugate (NGO-PEG-PEI) with ultra-small size. Compared with free PEI and the GO-P...

A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...

PLLA fibrous tissue scaffolds with controlled fiber nanoscale surface roughness are fabricated with a novel centrifugal jet spinning process. The centrifugal jet spinning technique is a highly efficient synthesis method for micron- to nano-sized fibers with a production rate up to 0.5 g min(-1). During the centrifugal jet spinning process, a polymer solution jet is stretched by the centrifugal ...

In this paper, the numerical simulation for nano-indentation is performed to measure time-dependent behavior of polymeric films. The possibility to extract the relaxed shear modulus of the polymer is evaluated using a rigid ball indenter. The viscoelastic behavior of the polymer was represented by the standard model. The effects of Poisson’s ratio are also discussed.

We have developed a self-consistent field theory of the effective interactions between nano-colloids mediated by adsorbing and non-adsorbing polymers. By making use of this theory, we have calculated the colloid immersion energy and the potential of the polymer-mediated forces for the above cases of polymer adsorption. On the basis of the obtained results for the polymer-mediated potentials, we...

polypyrrole is one of the most useful conductive polymers, but green synthesis of this polymer has been restricted until now. the objective of the present paper is green synthesis of nano polypyrrole (ppy) by oxidative polymerization using urea-hydrogen peroxide. it was found that conductivity and morphology of polypyrrole are highly dependent on the reaction conditions such as the molar ratio ...

Epoxy resin is extensively used in gas insulated switches as a renewable energy coating due to its exceptional insulation, mechanical characteristics, and environmental friendliness. The higher resistivity of the epoxy causes numerous surface charges accumulate on result carrier injection high DC electric field, which may cause insulation failure power transmission system. In this study, variou...