2. The first Hong Kong TDS aims to estimate the dietary exposure of the Hong Kong population and various population sub-groups to a range of substances and thus assess any associated health risks. The Study commenced in March 2010 and would be completed in 2014. As of December 2013, seven reports, covering “dioxins and dioxin-like polychlorinated biphenyls (PCBs)”, “inorganic arsenic”, “polybro...

In this study the mechanism of thyroid hormone reductions reported in rodents, following exposure to TCDD (Potter et al, 1983), PCBs (GrassIe and Biesmann 1982; Brouwer 1987) and polybrominated biphenyls (Gupta et al 1983), was investigated in rats at the level of the transport protein, transthyretin (TTR), using 3,4,3',4'-tetrachlorobiphenyl (TCB) as a model compound. Moreover, the effeets of ...

Concentrations of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) were measured in 23 seafood species widely consumed by the Korean population periods 2005–2007, 2010–2011, 2015–2017. The Σ82PCB (sum 82 PCB congeners) Σ19PBDE 19 PBDE concentrations samples 2015–2017 0.06–6.69 ng/g wet weight 0.01–1.60 weight, respectively. significantly correlated. Elevated found fat...

Previously we reported negative terata and c-mitosis synergism of FireMaster (polybrominated biphenyls) with colchicine in subacutely treated rats. Now we report absence of chromosome aberrations from FireMaster and absence of c-mitosis synergism of FireMaster and colchicine in male mice. For the study of chromosome aberrations groups of three mice received 0, 50, or 500 mg/kg FireMaster or 4.5...

In the early 1970s, the largest industrial accident in the United States resulted in widespread contamination of the food supply in Michigan with polybrominated biphenyls (PBBs). The chemical similarity of PBBs to compounds implicated as endocrine disruptors has raised the question of whether PBBs could affect the reproductive system. In the present analysis we examine the relation between seru...

Polybrominated biphenyl (PBB), a fire retardant, was accidentally substituted for an animal feed supplement in Michigan 10 years ago. This led to widespread livestock contamination and ultimately to contamination of virtually every human residing in the State at that time. In order to evaluate the extent of PBB persistence and distribution in human tissues 10 years after this accidental poisoni...