Pollen allergies have long been a major pandemic health problem for human. However, the evolutionary events and biological function of pollen allergens in plants remain largely unknown. Here, we report the genome-wide prediction of pollen allergens and their biological function in the dicotyledonous model plant Arabidopsis (Arabidopsis thaliana) and the monocotyledonous model plant rice (Oryza ...

BACKGROUND Conflicting results have been reported in studies of predictive factors for airway responsiveness to allergens during bronchial challenges. OBJECTIVE The aim of this study was to assess determinants of airway responsiveness to 3 different allergens during standardized bronchial challenges. METHODS Data were collected from asthmatic patients who participated in allergen challenge ...

It is estimated that pollen allergies affect approximately 40% of allergic individuals. In general, tree pollen allergies are mainly elicited by allergenic trees belonging to the orders Fagales, Lamiales, Proteales, and Pinales. Over 25 years ago, the gene encoding the major birch pollen allergen Bet v 1 was the first such gene to be cloned and its product characterized. Since that time, 53 tre...

Methods Monoclonal human IgE antibodies specific for the major birch pollen allergen Bet v 1 and for the major grass pollen allergen Phl p 5 and the corresponding allergens as well as a hybrid protein consisting of the Bet v 1 and Phl p 5 allergens were expressed. Using circular dichroism spectroscopy we compared the fold of the hybrid protein with that of the mixture of the two allergens. Rat ...

The pattern of food allergy in adults is different from that of children in various aspects. The typical foods involved in infants are milk, egg, peanut and probably tree nuts, whereas in older children and adults fruits and nuts are the most frequent allergenic foods. In addition, allergy to vegetables can occur. Allergy to milk and egg largely disappears at young age, but can still be present...

Abstracts of the XXII World Allergy Congress, 4–8 December, 2012 Cancún, Méxicos of the XXII World Allergy Congress, 4–8 December, 2012 Cancún, México ORAL ABSTRACT SESSION ALLERGEN IMMUNOTHERAPY 1 1 Ultra-Rush Specific Immune Therapy with Depigmented and Polymerized Allergen Extracts is Effective and Safe in Patients With Severe SAR Highly Sensitized against Pollen Allergens Michaela Gruber, a...

idea that profilin sensitization and profilin hypersensitivity prevalence in a particular area have the potential to predict the allergic inflammation level associated with grass pollinosis. Due to its association with the progression of grass pollinosis, profilin was thought to have limited clinical relevance in pediatric patients. In the paper by Asero et al. in this issue of International Ar...

Abstracts of the XXII World Allergy Congress, 4–8 December, 2012 Cancún, Méxicos of the XXII World Allergy Congress, 4–8 December, 2012 Cancún, México ORAL ABSTRACT SESSION ALLERGEN IMMUNOTHERAPY 1 1 Ultra-Rush Specific Immune Therapy with Depigmented and Polymerized Allergen Extracts is Effective and Safe in Patients With Severe SAR Highly Sensitized against Pollen Allergens Michaela Gruber, a...

Abstracts of the XXII World Allergy Congress, 4–8 December, 2012 Cancún, Méxicos of the XXII World Allergy Congress, 4–8 December, 2012 Cancún, México ORAL ABSTRACT SESSION ALLERGEN IMMUNOTHERAPY 1 1 Ultra-Rush Specific Immune Therapy with Depigmented and Polymerized Allergen Extracts is Effective and Safe in Patients With Severe SAR Highly Sensitized against Pollen Allergens Michaela Gruber, a...

Correction of an imbalance between allergen-specific T cell subsets is considered a critical event in establishing allergen tolerance by specific immunotherapy (SIT). In a comprehensive, longitudinal study, distinct T cell populations and Ig subtypes were analyzed in subjects allergic to birch pollen during decisive time points of SIT (i.e., induction and maintenance phase), as well as in and o...