STUDY QUESTION Is ovarian tissue cryopreservation using vitrification followed by in vitro activation (IVA) of dormant follicles a potential approach for infertility treatment of patients with primary ovarian insufficiency (POI)? SUMMARY ANSWER Our vitrification approach followed by IVA treatment is a potential infertility therapy for POI patients whose ovaries contain residual follicles. W...

MicroRNAs (miRNAs) post-transcriptionally regulate gene expression in animals and plants. The aim of this study was to investigate whether polymorphisms in miR-938 are associated with the risk of primary ovarian insufficiency (POI) and POI-related target gene regulation. We identified the miR-938G>A polymorphisms within the seed sequence of mature miRNA and aligned the seed sequence with the 3'...

This paper concerns versioning services over Semantic Web (SW) repositories. We propose a novel storage index (based on partial orders), called POI, that exploits the fact that RDF Knowledge Bases (KB) have not a unique serialization (as it happens with texts). POI can be used for storing several (versionrelated or not) SW KBs. We discuss the benefits and drawbacks of this approach in terms of ...

Point-of-Interest (POI) recommendation has been an important service on location-based social networks. However, it is very challenging to generate accurate recommendations due to the complex nature of user’s interest in POI and the data sparseness. In this paper, we propose a novel unified approach that could effectively learn fine-grained and interpretable user’s interest, and adaptively mode...

Context Caesarian section (CS) is one of the most common types of surgical procedure performed worldwide. Postoperative ileus (POI) is a recognised consequence of abdominal surgery, defined as the ‘transient cessation of coordinated bowel motility after surgical intervention, which prevents effective transit of intestinal contents and/or tolerance of intake’. POI is associated with delayed reco...

Postoperative ileus (POI) is a common clinical condition arising after almost every abdominal surgical procedure, leading to increased patient morbidity and prolonged hospitalisation. Recent advances in insight into the underlying pathophysiology have identified intestinal inflammation triggered by handling of the intestine as the main mechanism. Not only does the local inflammatory process com...

Next Point-of-Interest (POI) recommendation has become an important task for location-based social networks (LBSNs). However, previous efforts suffer from the high computational complexity, besides the transition pattern between POIs has not been well studied. In this paper, we proposed a twofold approach for next POI recommendation. First, the preferred next category is predicted by using a th...

With development of urban modernization, there are a large number of hop spots covering the entire city, defined as Pionts-of-Interest (POIs) Group consist of POIs. POI Groups have a significant impact on people’s lives and urban planning. Every person has her/his own personalized POI Groups (PPGs) based on preferences and friendship in location-based social networks (LBSNs). However, there are...

BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked heterogeneity, but with a significant genetic contribution. Identifying exact causative genes has been challenging, with many discoveries not replicated. It is timely to take stock of the field, outlining the progress made, framing the controversies and anticipating future directions in elucidating the genetics of POI. ...

Postoperative ileus (POI) increases morbidity and prolongs hospital stay after bowel resection. Alvimopan is a μ-antagonist designed to counteract gastrointestinal side effects of opiates without impairing analgesia due to its inability to pass the blood brain barrier. Because of its association with myocardial events in a long term study where it was applied to treat opiate-induced constipatio...