BACKGROUND: Health administrative data offer a vital source of on maternal prenatal opioid exposure (POE). The impact different methods to estimate POE, especially combining and newborn records, is not known. METHODS: This population-based cross-sectional study included 454 746 hospital births with linked in Ontario, Canada, 2014–2017. POE ascertainment 3 sources: (1) prescriptions, (2) opioid-...

Opiate addiction is now a major public health problem. Perinatal insults and exposure to opiates such as morphine in utero are well known to affect development of the hypothalamic-pituitary-adrenal axis of the offspring adversely and are associated with a higher risk of developing neurobehavioral problems. Oxycodone is now one of the most frequently abused pain killers during pregnancy; however...

A complete PDE sparse matrix solver consists of several components. Its overall performance strongly depends on their mutual interactions and the effect of application properties, especially when exploiting the parallelism of a distributed memory, message passing multiprocessor. This paper systematically investigates various aspects of the structure and performance of direct methods for solving...

Computer-based provider order entry (POE) can reduce the frequency of preventable medical errors. However, overly complex interfaces frequently pose a challenge to users and impede clinical efficacy. We present a cognitive analysis of clinician interaction with a commercial POE system. Our investigation was informed by the distributed resources model, a novel approach designed to describe the d...

Traditional methods based on the product of exponentials (POE) formula are parametrically continuous and complete for the calibration of the kinematic parameters of serial robots. However, these methods are not minimal due to the constraints of joint twists. This paper puts forward a new POE-based model, whose parameters are totally independent and conform to the formula of minimality. This is ...

In many cases, polyol ester (POE) and polyalkylene glycol (PAG) lubricants used with HFC refrigerants, may cause long-term reliability and stability problems. Mineral oil lubricants are much more stable in the long run and do not suffer from stability problems nearly as much as POE and PAG lubricants. HFC based refrigerants and blends are, in general, nonmiscible in mineral oils, and will not r...

Different designs have been presented to achieve high concentration and uniformity for the concentrated photovoltaic (CPV) system. Most of the designs have issues of low efficiency in terms of irradiance uniformity. To this end, we present a design methodology to increase irradiance uniformity over solar cell. The system consists of an eight-fold Fresnel lens as a primary optical element (POE) ...

A test method that measures spectrally resolved irradiance distribution for a concentrator photovoltaic (CPV) optical system is presented. In conjunction with electrical I-V curves, it is a means to visualize and characterize the effects of chromatic aberration and nonuniform flux profiles under controllable testing conditions. The indoor characterization test bench, METHOD (Measurement of Elec...

Enzymatic synthesis of palm oil esters (POE) was carried out via alcoholysis of palm oil (PO) and oleyl alcohol (OA) catalyzed by Lipozyme TL IM. The optimum reaction conditions were: temperature: 60 °C; enzyme load: 24.7 wt%; substrate ratio: 1:3 (PO/OA), impeller speed: 275 rpm and reaction time: 3 h. At the optimum condition, the conversion of POE was 79.54%. Reusability study showed that Li...

A field experiment was conducted during the rainy (kharif) season of 2019 at ICAR-Indian Agricultural Research Institute, New Delhi, to study effect different tillage and weed-management practices on productivity, water energy-use efficiency pearl millet [Pennisetum glaucum (L.). R. Br.]. The laid out in a split-plot design, with main plot, viz. conventional (CT), zero (ZT), + residue (ZT R) 3 ...