Pleomorphic adenoma is the most common benign tumor of the parotid glands. Rarely it may arise from minor salivary glands of the upper aerodigestive tract. A 57-year-old woman was admitted at our institution presenting with nasal obstruction. Endoscopic evaluation revealed a pedicled mass in the rhinopharynx. After radiological examination, we opted for a transnasal endoscopic-assisted excision...

Pleomorphic adenoma directly arising in the neck is thought to originate from heterotopic salivary gland tissue. In this article, we present the case of a 55-year-old female patient with a histologically proven pleomorphic adenoma located at the left mandibular angle, anteriorly to the sternocleidomastoid muscle and posteroinferiorly to the submandibular gland. As the patient also had an ipsila...

Primary carcinoma ex pleomorphic adenoma in the tracheobronchial system is an exceedingly rare neoplasm arising from minor salivary glands. Two cases of this unusual entity were presented. All the lesions were associated with bronchial system, while neither of the patients had a history of a head and neck salivary gland neoplasm. Both cases were followed up for more than 3.5 years. Thus, furthe...

Differentially expressed genes in various benign and malignant salivary gland tumours were identified by use of cDNA microarrays containing 19,000 human expressed sequence tags. Samples were derived from 5 patients with pleomorphic adenoma, 4 with Warthin's tumour, one with clear cell carcinoma, and 2 with mucoepidermoid carcinoma. Tumours were classified by using a subset of 486 genes. Benign ...

Pleomorphic adenoma is the commonest type of all benign and malignant salivary gland neoplasm majority involving the parotid gland. It is a slow growing and benign tumour which can reach an enourmous size and may turn malignant if left untreated. Although uncommon, most cases of giant pleomorphic adenoma were reported before 1980’s, with few publications recently. This paper presents a rare cas...

Pleomorphic adenomas are the most common tumors of the salivary glands. Rarely, they occur as benign lesions in the lungs in both the central airways and the lung parenchyma. Herein, we present a case of a 60-year-old smoker who was incidentally found to have an endobronchial mass while undergoing evaluation for a lung nodule. During bronchoscopy, a smooth globular nodule was identified at the ...