The effective resolution of human platelet cytosolic phosphoinositide-phospholipase C (PLC) revealed five distinct activity peaks by Q-Sepharose and heparin-Sepharose column chromatographies when assayed using phosphatidylinositol (PI) and phosphatidylinositol 4,5-bisphosphate (PIP2). The results of Western blotting analysis with various antibodies against PLC isozymes showed that peak-Ia (PLC-...

We report a unique isoform of PLC[beta]4 in rat, PLC[beta]4c, that has an additional 37nucleotide exon inserted between nucleotides 3459-3460 of the previously published PLC[beta]4a coding sequence. This insertion results in replacement of 22 amino acid residues at the carboxyl terminal tail of PLC[beta]4a with 41 unique residues. A human EST for PLC[beta]4 also contains this exon and this exon...

Studies of ribosomal proteins have given insight to the function and structure of the ribosome. During ribosome assembly, individual ribosomal proteins that initially recognize rRNA must bind to the assembly particle in a certain order and work cooperatively, rather than independently (1). Two of these important ribosomal proteins are S7 and S8. Detailed study of these and other ribosomal prote...

We present DeepISP, a full end-to-end deep neural model of the camera image signal processing (ISP) pipeline. Our model learns a mapping from the raw low-light mosaiced image to the final visually compelling image and encompasses low-level tasks such as demosaicing and denoising as well as higher-level tasks such as color correction and image adjustment. The training and evaluation of the pipel...

In this article, a speed control of DC motor is designed and illustrated using fuzzy logic-based programmable logic controller (PLC). The DC motor is an attractive part of electrical equipment in many industrial applications requiring variable speed and load specifications due to its ease of controllability. The designed system is consisted of three main parts including programmable logic contr...

Four different isoforms of phospholipase C-beta (PLC-beta 1-4) have been discovered, raising the important question of whether a distinct receptor activates a single PLC-beta isoenzyme or a subset of PLC-beta isoenzymes. The present study was designed to investigate activation of PLC-beta isoenzymes by three different PLC-activating agonists that bind to different receptor entities, i.e., chole...