Riboswitches sense cellular concentrations of small molecules and use this information to adjust synthesis rates of related metabolites. Riboswitches include an aptamer domain to detect the ligand and an expression platform to control gene expression. Previous structural studies of riboswitches largely focused on aptamers, truncating the expression domain to suppress conformational switching. T...

This paper proposes two new soft-switching transformerless converters with high voltage conversion ratio. These proposed converters achieve soft-switching each with a single auxiliary resonant cell. The merit of these converters is reduced switching losses with lesser number of devices. The main switching devices are turned off with zero current switching (ZCS). Apart from the soft-switching fe...

This study focuses on the robust control of stabilized platform of rotary steering drilling system. Firstly, the uncertain and nonlinear mathematical model of stabilized platform is given by considering the outside interference, drilling technology and geometrical parameter perturbation of the borehole on stabilized platform under work condition. Then, an adaptive neural network sliding mode co...

OBJECTIVES The objective of this work was to use finite element analysis to compare the effect of forces coming to bear on abutments 4.1 or 5.0 mm in diameter connected to a 5.0 mm implant (i.e. with or without platform switching). STUDY DESIGN A 3D CAD model of a 5 x 11.5 mm external hex implant was developed, complete with a connection screw and either of two abutments, one 4.1 and the othe...

Efficient temperature-sensing platform was demonstrated using temperature-responsive, fluorescent P7AC-b-PNIPAM-b-PSN3 block copolymer-anchored graphene oxide sheets (FGO). FGO exhibited extraordinary stability in water and showed fast optical on-off switching behavior in response to temperature change.

We demonstrate highly efficient evanescent coupling between a highly nonlinear chalcogenide glass two dimensional photonic crystal waveguide and a silica fiber nanowire. We achieve 98% insertion efficiency to the fundamental photonic crystal waveguide mode with a 3dB coupling bandwidth of 12nm, in good agreement with theory. This scheme provides a promising platform to realize low power nanocav...

Two-dimensional (2D) nanomaterials are an emergent and promising platform for future photonic and optoelectronic applications. Here, we review recent progress demonstrating the application of 2D nanomaterials as versatile, wideband saturable absorbers for Q-switching and mode-locking fibre lasers. We focus specifically on the family of few-layer transition metal dichalcogenides, including MoS2,...