Novel imaging techniques using biomarkers have clarified the mechanisms of hitherto unanswered or misunderstood phenomena of coronary artery disease and enabled evaluation of myocardial blood and tissue fluid flows in vivo. Dye-staining coronary angioscopy using Evans blue (EB) as the biomarker can visualize fibrin and damaged endothelial cells, revealing that the so-called platelet thrombus is...

Purpose: The purpose of this study is to check up the possible usage of a new approach when treating oroantral communication (OAC) which includes the usage of platelet-rich fibrin (PRF). Methods and materials: 6 patients (4 women and 2 men) participated in this study with oroantral communications after the extractions of maxillary molars. The OAC was closed surgically using PRF membranes. The c...

The filling of tissue for facial rejuvenation can be challenging. The aim is to restore harmonious volumetric facial ratios by regaining the contours of cheekbones, drooping jaw lines and nasolobial folds. Adipocyte grafts can return the skin to a state of brightness and to a volume that deteriorates gradually during ageing. To ensure that a tissue graft remains stable, it must be integrated in...

Recently, by employing intra-vital confocal microscopy, we demonstrated that platelets expose phosphatidylserine (PS) and fibrin accumulate only in the center of the thrombus but not in its periphery. To address the question how exposure of platelet anionic phospholipids is regulated within the thrombus, an in-vitro experiment using diluted platelet-rich plasma was employed, in which the fibrin...