Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. This study was conducted to determine microparticles formation and platelet shrinkage ...

Obesity in children is becoming a global epidemic. Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent and potentially serious complication of childhood obesity. Adiponectin level was decreased on obese children. Adiponectin is a protective factor against non-alcoholic fatty liver disease on obesity. The early identification of fibrosis is important in children with NAFLD in order to...

Objective 
 This study aimed to determine the predictability of platelet mass index (PMI) for short-term mortality in patients with COVID 19.
 Material and methods
 retrospective, observational, cohort included corrected COVID-19 patients. Demographics, clinical characteristics, biochemical hematological parameters data all-cause within 30 days after admission were noted. The rec...

The effect of oestrogen-containing compounds on platelet factor 3, platelet life span, renal platelet localization and the fibrinolytic activity of forearm venous blood has been studied in eleven women with the renal vascular abnormalities of the loin pain and haematuria syndrome. The results were compared with those obtained in twenty-nine healthy female volunteer subjects. 2. Platelet factor ...

Mean platelet volume has been proposed as a predictor for venous thromboembolism in cancer. We, therefore, investigated the effects of different anti-cancer drugs on mean platelet volume in order to assess its possible value in the risk prediction of a first thromboembolic episode in cancer outpatients during treatment. Pre-treatment mean platelet volumes were retrospectively evaluated in 589 a...

BACKGROUND AND PURPOSE Platelet activation plays a crucial role in the pathophysiology of cerebral ischemia. The aim of this study was to investigate the contribution of platelet activation and leukocyte-platelet interactions to the disease. METHODS One hundred thirty-five patients with transient ischemic attack (TIA) or stroke were enrolled in this single-center study. They underwent cranial...

Aim: The aim of this study was to determine the usefulness systemic immune-inflammation index (SII) in diagnosis acute appendicitis (AA) children 
 Material and Method: This done retrospectively, two groups were formed as AA control group. group divided into subgroups nonperforated perforated appendicitis. compared for age, sex, WBC, neutrophil, lymphocyte platelet count, neutrophil-to-lym...

background: platelet mps are produced automatically during platelet storage. their size is about 0.1 – 1 µm and have ability for sub- endothelium adhering, strengthen of platelet aggregation and also platelet pre- coagulation. in fact, the release of membrane particles helps to signal to the neighbor cells or to seclude target cells from apoptosis. the purpose of this study is to determine the ...

background: the autoimmune disease known as idiopathic (immune thrombocytopenic purpura thrombocytopenic purpura (itp) is clinically defined by a low numbers of platelets in the circulation blood. this study aimed to isolate autoantibodies made against the platelet glycoproteins using platelets from healthy volunteers, to determine their specificity and further elucidate their effects on platel...